Literature DB >> 16091121

CD4+CD25+-regulatory T cells from mouse to man.

K Wing1, E Suri-Payer, A Rudin.   

Abstract

Immunological tolerance is one of the fundamental concepts of the immune system. During the past decade, CD4+CD25+-regulatory T cells have emerged as key players in the development of tolerance to autoantigens as well as to foreign antigens. Still many questions remain illusive regarding the basic properties of CD4+CD25+-regulatory T cells. This review aims to recapitulate some of the current understandings about the phenotype, function and clinical relevance of murine and human CD4+CD25+-regulatory T cells.

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Year:  2005        PMID： 16091121     DOI： 10.1111/j.1365-3083.2005.01634.x

Source DB:  PubMed          Journal:  Scand J Immunol        ISSN： 0300-9475            Impact factor:   3.487


  12 in total

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