Literature DB >> 16087912

The chemokine CXCL13 (BLC): a putative diagnostic marker for neuroborreliosis.

T A Rupprecht1, H W Pfister, B Angele, S Kastenbauer, B Wilske, U Koedel.   

Abstract

Using protein expression profiling, the authors identified an upregulation of the chemokine B lymphocyte chemoattractant (BLC) in the CSF of patients with neuroborreliosis but not in patients with noninflammatory and various other inflammatory neurologic diseases. This upregulation was confirmed by ELISA, showing increased BLC levels in every neuroborreliosis patient while being undetectable in patients with noninflammatory neurologic diseases. These results point to BLC as a putative additional diagnostic marker for neuroborreliosis.

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Year:  2005        PMID： 16087912     DOI： 10.1212/01.wnl.0000171349.06645.79

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  50 in total

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