Literature DB >> 16086723

Antireflux surgery outcomes in pediatric gastroesophageal reflux disease.

Diego M Diaz1, Troy E Gibbons, Kurt Heiss, Mark L Wulkan, Richard R Ricketts, Benjamin D Gold.   

Abstract

OBJECTIVES: Antireflux surgery is performed frequently in children with gastroesophageal reflux disease (GERD). Few comparative studies exist which assess the indications for and short- or long-term outcome of open Nissen fundoplication (ONF) and laparoscopic Nissen fundoplication (LNF) for pediatric GERD. We investigated the frequency of reoperation and factors that might influence its occurrence.
METHODS: We performed a retrospective, follow up cohort study of all children </=5 years, who underwent LNF or ONF at our institution from January 1, 1997 to December 31, 2002, where five pediatric surgeons perform fundoplication. Mean follow up time was 36.2 months. The following information was obtained: surgical indications, hospital course data, and long-term surgical outcomes. Data were analyzed using univariate and multiple logistic regressions.
RESULTS: Overall, 456 (150 [32.9%] ONF vs. 306 [67.1%] LNF) cases were analyzed. Reoperation was performed in 55 (12.06%), LNF 43 (14.05%), and ONF 12 (8%). The mean interim to reoperation for LNF was 11 months compared to 17 months for ONF (p= 0.007). The reoperation rate at 12 and 24 months were 10.5%, 13.4% and 4%, 6.7% respectively, when LNF was compared to ONF (p= 0.01). The multivariate analysis showed that initial LNF and prematurity were the main predictors for reoperation.
CONCLUSIONS: The majority of reoperations for both LNF and ONF occurred in the first year after initial operation; LNF had a significantly higher reoperation rate than ONF. The probability of reoperation for LNF and ONF increases with the presence of comorbidities, especially prematurity and chronic respiratory conditions.

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Mesh:

Year:  2005        PMID: 16086723     DOI: 10.1111/j.1572-0241.2005.41763.x

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   10.864


  14 in total

1.  Anti-gastroesophageal reflux surgery in infants with severe bronchopulmonary dysplasia.

Authors:  Erik A Jensen; David A Munson; Huayan Zhang; Thane A Blinman; Haresh Kirpalani
Journal:  Pediatr Pulmonol       Date:  2014-04-21

2.  Laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease in infants.

Authors:  Ling Leung; Carol Wing Yan Wong; Patrick Ho Yu Chung; Kenneth Kak Yuen Wong; Paul Kwong Hang Tam
Journal:  Pediatr Surg Int       Date:  2014-10-28       Impact factor: 1.827

3.  Impact of prior surgery on the feasibility of laparoscopic surgery for children: a prospective study.

Authors:  M L Metzelder; N Jesch; A Dick; J Kuebler; C Petersen; B M Ure
Journal:  Surg Endosc       Date:  2006-10-05       Impact factor: 4.584

Review 4.  Gastroesophageal reflux disease in children and adolescents: when and how to treat.

Authors:  Matthew W Carroll; Kevan Jacobson
Journal:  Paediatr Drugs       Date:  2012-04-01       Impact factor: 3.022

5.  A meta-analysis of outcomes after open and laparoscopic Nissen's fundoplication for gastro-oesophageal reflux disease in children.

Authors:  Muhammad Rafay Sameem Siddiqui; Y Abdulaal; A Nisar; H Ali; F Hasan
Journal:  Pediatr Surg Int       Date:  2010-08-24       Impact factor: 1.827

6.  Outcomes of laparoscopic nissen fundoplications in children younger than 2-years: single institution experience.

Authors:  Armando Rosales; Jill Whitehouse; Carrie Laituri; Glenda Herbello; Julie Long
Journal:  Pediatr Surg Int       Date:  2018-05-28       Impact factor: 1.827

7.  Outcomes of laparoscopic versus open fundoplication in children's hospitals: 2005-2008.

Authors:  David Fox; Elaine Morrato; Elizabeth J Campagna; Daniel I Rees; L Miriam Dickinson; David A Partrick; Allison Kempe
Journal:  Pediatrics       Date:  2011-04-18       Impact factor: 7.124

Review 8.  Outcomes of pediatric laparoscopic fundoplication: a critical review of the literature.

Authors:  Kathryn Martin; Catherine Deshaies; Sherif Emil
Journal:  Can J Gastroenterol Hepatol       Date:  2013-11-28

Review 9.  Step-up and step-down approaches to treatment of gastroesophageal reflux disease in children.

Authors:  Eric Hassall
Journal:  Curr Gastroenterol Rep       Date:  2008-06

10.  Outcomes of fundoplication for paediatric gastroesophageal reflux disease.

Authors:  E Pascoe; T Falvey; A Jiwane; G Henry; U Krishnan
Journal:  Pediatr Surg Int       Date:  2015-12-08       Impact factor: 1.827

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