| Literature DB >> 16086254 |
Abstract
Keratinocyte growth factor-2 (KGF-2) is found in dermal papilla fibroblasts and its receptor, fibroblast growth factor receptor 2 (FGFR2), in the neighboring outer root sheath of keratinocytes. Administration of recombinant human KGF-2 (rhKGF-2) at 10 ng ml(-1) significantly stimulated human hair-follicle cell proliferation in organ culture (26-35%). Thus, rhKGF-2 is a promising therapeutic agent to stimulate human hair growth.Entities:
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Year: 2005 PMID: 16086254 DOI: 10.1007/s10529-005-5624-y
Source DB: PubMed Journal: Biotechnol Lett ISSN: 0141-5492 Impact factor: 2.461