Literature DB >> 16084770

Current drug development portfolio for antimalarial therapies.

Giancarlo A Biagini1, Paul M O'Neill, Patrick G Bray, Stephen A Ward.   

Abstract

In response to the emergence of parasite drug resistance to currently deployed antimalarials, the scientific community, in partnership with the pharmaceutical industry and public organizations, has fashioned an antimalarial drug development portfolio for the sustained development and registration of safe, effective and cheap antimalarial medicines. The management of this portfolio is being driven by MMV (Medicines for Malaria Venture), with a number of projects recently reaching the clinical end of this drug development pipeline.

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Year:  2005        PMID: 16084770     DOI: 10.1016/j.coph.2005.05.004

Source DB:  PubMed          Journal:  Curr Opin Pharmacol        ISSN: 1471-4892            Impact factor:   5.547


  3 in total

Review 1.  Resisting resistance: dealing with the irrepressible problem of malaria.

Authors:  Geoffrey Edwards; Giancarlo A Biagini
Journal:  Br J Clin Pharmacol       Date:  2006-06       Impact factor: 4.335

2.  β-amino-alcohol tethered 4-aminoquinoline-isatin conjugates: synthesis and antimalarial evaluation.

Authors:  Jiri Gut; Philip J Rosenthal; Vipan Kumar
Journal:  Eur J Med Chem       Date:  2014-07-21       Impact factor: 6.514

3.  Continued cytoadherence of Plasmodium falciparum infected red blood cells after antimalarial treatment.

Authors:  Katie R Hughes; Giancarlo A Biagini; Alister G Craig
Journal:  Mol Biochem Parasitol       Date:  2009-10-01       Impact factor: 1.759

  3 in total

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