OBJECTIVE: To analyze the construct validity of the EQ-5D in patients with acute coronary syndromes (ACS). METHODS: All ACS-diagnosed patients discharged from a university-affiliated hospital during a 3-year period were mailed a questionnaire that included the EQ-5D and the SF-8. The EQ-5D includes a visual analogue scale (EQ VAS) to measure self-reported current health-status (0-100) and a five-item descriptive system measuring mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Also included were disease severity measures [Duke Activity Status Index (DASI), cardiac symptom count (SC), patient-perceived cardiac disease severity], comorbidity measures (Charlson comorbidity index, total medication count), and other demographic and disease-related items. RESULTS: Of 1217 patients, 490 (40.3%) responded. Patients averaged 65.2 (SD 11.3) years of age; 71.0% male; 91.9% Caucasian; 64.3% history of MI. Only 0.2%-0.4% of EQ-5D items and 8% of the EQ VAS were left unanswered by respondents. The nine most common health states were identified based on the five EQ-5D item scores. Levels of responses to EQ-5D items and the EQ VAS score were significantly better for patients with very mild/mild perceived disease severity compared to severe/very severe, for patients with lower comorbidity, for patients with lower symptom responses, and for patients with a higher cardiac-related functioning. EQ VAS score and SF-8 subscale score correlation coefficients ranged from 0.527 to 0.798 (all p < 0.0001). Significant differences were observed between the response level of individual EQ-5D items and scores of comparable SF-8 subscales. CONCLUSIONS: This study demonstrated the construct validity of the EQ-5D in a population-based sample of patients with a history of ACS.
OBJECTIVE: To analyze the construct validity of the EQ-5D in patients with acute coronary syndromes (ACS). METHODS: All ACS-diagnosed patients discharged from a university-affiliated hospital during a 3-year period were mailed a questionnaire that included the EQ-5D and the SF-8. The EQ-5D includes a visual analogue scale (EQ VAS) to measure self-reported current health-status (0-100) and a five-item descriptive system measuring mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Also included were disease severity measures [Duke Activity Status Index (DASI), cardiac symptom count (SC), patient-perceived cardiac disease severity], comorbidity measures (Charlson comorbidity index, total medication count), and other demographic and disease-related items. RESULTS: Of 1217 patients, 490 (40.3%) responded. Patients averaged 65.2 (SD 11.3) years of age; 71.0% male; 91.9% Caucasian; 64.3% history of MI. Only 0.2%-0.4% of EQ-5D items and 8% of the EQ VAS were left unanswered by respondents. The nine most common health states were identified based on the five EQ-5D item scores. Levels of responses to EQ-5D items and the EQ VAS score were significantly better for patients with very mild/mild perceived disease severity compared to severe/very severe, for patients with lower comorbidity, for patients with lower symptom responses, and for patients with a higher cardiac-related functioning. EQ VAS score and SF-8 subscale score correlation coefficients ranged from 0.527 to 0.798 (all p < 0.0001). Significant differences were observed between the response level of individual EQ-5D items and scores of comparable SF-8 subscales. CONCLUSIONS: This study demonstrated the construct validity of the EQ-5D in a population-based sample of patients with a history of ACS.
Authors: Robin Mathews; Eric D Peterson; Emily Honeycutt; Chee Tang Chin; Mark B Effron; Marjorie Zettler; Gregg C Fonarow; Timothy D Henry; Tracy Y Wang Journal: Circ Cardiovasc Qual Outcomes Date: 2015-06-02
Authors: Rachel P Dreyer; Kim G Smolderen; Kelly M Strait; John F Beltrame; Judith H Lichtman; Nancy P Lorenze; Gail D'Onofrio; Héctor Bueno; Harlan M Krumholz; John A Spertus Journal: Eur Heart J Acute Cardiovasc Care Date: 2015-02-13
Authors: Amit P Amin; Alok Bachuwar; Kimberly J Reid; Adnan K Chhatriwalla; Adam C Salisbury; Robert W Yeh; Mikhail Kosiborod; Tracy Y Wang; Karen P Alexander; Kensey Gosch; David J Cohen; John A Spertus; Richard G Bach Journal: J Am Coll Cardiol Date: 2013-03-26 Impact factor: 24.094
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Authors: Rachel P Dreyer; Yongfei Wang; Kelly M Strait; Nancy P Lorenze; Gail D'Onofrio; Héctor Bueno; Judith H Lichtman; John A Spertus; Harlan M Krumholz Journal: Circulation Date: 2015-04-10 Impact factor: 29.690
Authors: Kimberley A Goldsmith; Matthew T Dyer; Martin J Buxton; Linda D Sharples Journal: Health Qual Life Outcomes Date: 2010-06-04 Impact factor: 3.186
Authors: Kimberley A Goldsmith; Matthew T Dyer; Peter M Schofield; Martin J Buxton; Linda D Sharples Journal: Health Qual Life Outcomes Date: 2009-11-26 Impact factor: 3.186