The influence of varying blood and dialysate flow on haemodialysis adequacy.

The aim of this study was the exploration and correlation of the influence of variations in blood flow and dialysate flow on haemodialysis adequacy through the quantitative indexes Kt/V, TACurea and PCR. A prospective study of 48 patients subjected to haemodialysis was carried out. The collection of data included taking blood and urine samples according to the directives of DOQI, for a total of 8 months. Statistical analysis was based on the paired t-test and multiple regression analysis. The variations in blood flow and dialysate flow are positively related to the variation of the indexes Kt/V, TACurea and PCR and consequently to the haemodialysis adequacy both as isolated factors and when combined together.