Literature DB >> 16078938

Towards a better understanding of abdominal bloating and distension in functional gastrointestinal disorders.

L A Houghton1, P J Whorwell.   

Abstract

Abdominal bloating is an extremely common symptom affecting up to 96% of patients with functional gastrointestinal disorders and even 30% of the general population. To date bloating has often been viewed as being synonymous with an actual increase in abdominal girth, but recent evidence suggests that this is not necessarily the case. This review examines the relationship between the symptom of bloating and the physical sign of abdominal distension, as well as examining the epidemiology, pathophysiology and treatment options available for this debilitating aspect of the functional gastrointestinal disorders. Pathophysiological mechanisms explored include psychological factors, intestinal gas accumulation, fluid retention, food intolerance and malabsorption of sugars, weakness of abdominal musculature, and altered sensorimotor function. Treatment options are currently rather limited but include dietary changes, pharmacological approaches, probiotics and hypnotherapy.

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Year:  2005        PMID: 16078938     DOI: 10.1111/j.1365-2982.2005.00666.x

Source DB:  PubMed          Journal:  Neurogastroenterol Motil        ISSN: 1350-1925            Impact factor:   3.598


  15 in total

1.  The challenge of developing new therapies for irritable bowel syndrome.

Authors:  Fernando Azpiroz; Peter J Whorwell
Journal:  Therap Adv Gastroenterol       Date:  2009-07       Impact factor: 4.409

2.  Prevalence and risk factors for abdominal bloating and visible distention: a population-based study.

Authors:  X Jiang; G R Locke; R S Choung; A R Zinsmeister; C D Schleck; N J Talley
Journal:  Gut       Date:  2008-06       Impact factor: 23.059

3.  Health care seeking for abdominal bloating and visible distention.

Authors:  X Jiang; G R Locke; A R Zinsmeister; C D Schleck; N J Talley
Journal:  Aliment Pharmacol Ther       Date:  2009-06-25       Impact factor: 8.171

4.  Bloating in Irritable Bowel Syndrome Is Associated with Symptoms Severity, Psychological Factors, and Comorbidities.

Authors:  Keren Hod; Yehuda Ringel; Miranda A L van Tilburg; Tamar Ringel-Kulka
Journal:  Dig Dis Sci       Date:  2018-12-18       Impact factor: 3.199

Review 5.  Abdominal bloating and distension: what is the role of the microbiota.

Authors:  B Issa; N A Wafaei; P J Whorwell
Journal:  Dig Dis Sci       Date:  2011-07-29       Impact factor: 3.199

6.  Management Strategies for Abdominal Bloating and Distension.

Authors:  Anna Foley; Rebecca Burgell; Jacqueline S Barrett; Peter R Gibson
Journal:  Gastroenterol Hepatol (N Y)       Date:  2014-09

7.  Current gut-directed therapies for irritable bowel syndrome.

Authors:  Howard Y Chang; Eoin C Kelly; Anthony J Lembo
Journal:  Curr Treat Options Gastroenterol       Date:  2006-07

8.  Bloating in Iran: SEPAHAN Systematic Review No. 4.

Authors:  Parnaz Daneshpajouhnejad; Ammar Hassanzadeh Keshteli; Shirin Sadeghpour; Samaneh Khanpour Ardestani; Peyman Adibi
Journal:  Int J Prev Med       Date:  2012-03

Review 9.  Abdominal bloating: pathophysiology and treatment.

Authors:  A Young Seo; Nayoung Kim; Dong Hyun Oh
Journal:  J Neurogastroenterol Motil       Date:  2013-10-07       Impact factor: 4.924

Review 10.  Guidelines on the irritable bowel syndrome: mechanisms and practical management.

Authors:  R Spiller; Q Aziz; F Creed; A Emmanuel; L Houghton; P Hungin; R Jones; D Kumar; G Rubin; N Trudgill; P Whorwell
Journal:  Gut       Date:  2007-05-08       Impact factor: 23.059

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