| Literature DB >> 16077101 |
Ana Tereza R Vasconcelos1, Henrique B Ferreira, Cristiano V Bizarro, Sandro L Bonatto, Marcos O Carvalho, Paulo M Pinto, Darcy F Almeida, Luiz G P Almeida, Rosana Almeida, Leonardo Alves-Filho, Enedina N Assunção, Vasco A C Azevedo, Maurício R Bogo, Marcelo M Brigido, Marcelo Brocchi, Helio A Burity, Anamaria A Camargo, Sandro S Camargo, Marta S Carepo, Dirce M Carraro, Júlio C de Mattos Cascardo, Luiza A Castro, Gisele Cavalcanti, Gustavo Chemale, Rosane G Collevatti, Cristina W Cunha, Bruno Dallagiovanna, Bibiana P Dambrós, Odir A Dellagostin, Clarissa Falcão, Fabiana Fantinatti-Garboggini, Maria S S Felipe, Laurimar Fiorentin, Gloria R Franco, Nara S A Freitas, Diego Frías, Thalles B Grangeiro, Edmundo C Grisard, Claudia T Guimarães, Mariangela Hungria, Sílvia N Jardim, Marco A Krieger, Jomar P Laurino, Lucymara F A Lima, Maryellen I Lopes, Elgion L S Loreto, Humberto M F Madeira, Gilson P Manfio, Andrea Q Maranhão, Christyanne T Martinkovics, Sílvia R B Medeiros, Miguel A M Moreira, Márcia Neiva, Cicero E Ramalho-Neto, Marisa F Nicolás, Sergio C Oliveira, Roger F C Paixão, Fábio O Pedrosa, Sérgio D J Pena, Maristela Pereira, Lilian Pereira-Ferrari, Itamar Piffer, Luciano S Pinto, Deise P Potrich, Anna C M Salim, Fabrício R Santos, Renata Schmitt, Maria P C Schneider, Augusto Schrank, Irene S Schrank, Adriana F Schuck, Hector N Seuanez, Denise W Silva, Rosane Silva, Sérgio C Silva, Célia M A Soares, Kelly R L Souza, Rangel C Souza, Charley C Staats, Maria B R Steffens, Santuza M R Teixeira, Turan P Urmenyi, Marilene H Vainstein, Luciana W Zuccherato, Andrew J G Simpson, Arnaldo Zaha.
Abstract
This work reports the results of analyses of three complete mycoplasma genomes, a pathogenic (7448) and a nonpathogenic (J) strain of the swine pathogen Mycoplasma hyopneumoniae and a strain of the avian pathogen Mycoplasma synoviae; the genome sizes of the three strains were 920,079 bp, 897,405 bp, and 799,476 bp, respectively. These genomes were compared with other sequenced mycoplasma genomes reported in the literature to examine several aspects of mycoplasma evolution. Strain-specific regions, including integrative and conjugal elements, and genome rearrangements and alterations in adhesin sequences were observed in the M. hyopneumoniae strains, and all of these were potentially related to pathogenicity. Genomic comparisons revealed that reduction in genome size implied loss of redundant metabolic pathways, with maintenance of alternative routes in different species. Horizontal gene transfer was consistently observed between M. synoviae and Mycoplasma gallisepticum. Our analyses indicated a likely transfer event of hemagglutinin-coding DNA sequences from M. gallisepticum to M. synoviae.Entities:
Mesh：
Year: 2005 PMID： 16077101 PMCID： PMC1196056 DOI： 10.1128/JB.187.16.5568-5577.2005
Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490