Hyaluronic acid--syneretic glycosaminoglycan.

Hyaluronic acid from different sources, umbilical cord, vitreous, rooster comb and streptococcus, all exhibit a unique hydration behavior. Each hyaluronic acid and each different salt form has a maximum non-freezable water content at a set concentration beyond which the bound (non-freezable) water decreases. This type of behavior indicates a syneretic process simply due to concentration alone.