| Literature DB >> 1606565 |
E Donti1, A Maccari, A Tabilio, C Ardisia, N Campanari, G V Donti.
Abstract
Two patients with M2 subtype of acute nonlymphocytic leukemia (ANLL) and trisomy 4 as a primary karyotype change are described. The abnormality was observed in 100% of bone marrow (BM) metaphases in both cases. It appeared alone in one case and was associated with trisomy 13 in 94% of metaphases in the other. These are the second and third cases of ANLL with trisomy 4 documented in Italy. Neither patient appears to have incurred any environmental or therapeutic insult.Entities:
Mesh：
Year: 1992 PMID： 1606565 DOI： 10.1016/0165-4608(92)90018-4
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608