Literature DB >> 16064138

Transcriptional regulation and transformation by Myc proteins.

Sovana Adhikary1, Martin Eilers.   

Abstract

Myc genes are key regulators of cell proliferation, and their deregulation contributes to the genesis of most human tumours. Recently, a wealth of data has shed new light on the biochemical functions of Myc proteins and on the mechanisms through which they function in cellular transformation.

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Year:  2005        PMID： 16064138     DOI： 10.1038/nrm1703

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  455 in total

1.  Aberrant signaling pathways in pancreatic cancer: a two compartment view.

Authors:  Angela L McCleary-Wheeler; Robert McWilliams; Martin E Fernandez-Zapico
Journal:  Mol Carcinog       Date:  2012-01       Impact factor: 4.784

Review 2.  Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development.

Authors:  W-L Yang; X Zhang; H-K Lin
Journal:  Oncogene       Date:  2010-06-07       Impact factor: 9.867

3.  Transcriptional repression of Mad-Max complex by human umbilical cord blood stem cells downregulates extracellular signal-regulated kinase in glioblastoma.

Authors:  Kiran Kumar Velpula; Venkata Ramesh Dasari; Andrew J Tsung; Dzung H Dinh; Jasti S Rao
Journal:  Stem Cells Dev       Date:  2011-11-21       Impact factor: 3.272

4.  Excessive hepatomegaly of mice with hepatocyte-targeted elimination of integrin linked kinase following treatment with 1,4-bis [2-(3,5-dichaloropyridyloxy)] benzene.

Authors:  Shashikiran Donthamsetty; Vishakha S Bhave; Corrine S Kliment; William C Bowen; Wendy M Mars; Aaron W Bell; Rachel E Stewart; Anne Orr; Chuanyue Wu; George K Michalopoulos
Journal:  Hepatology       Date:  2011-01-06       Impact factor: 17.425

5.  c-Myc regulates RNA splicing of the A-Raf kinase and its activation of the ERK pathway.

Authors:  Jens Rauch; Kim Moran-Jones; Valerie Albrecht; Thomas Schwarzl; Keith Hunter; Olivier Gires; Walter Kolch
Journal:  Cancer Res       Date:  2011-04-21       Impact factor: 12.701

6.  Epigenetic reprogramming of Myc target genes.

Authors:  Stefano Amente; Luigi Lania; Barbara Majello
Journal:  Am J Cancer Res       Date:  2011-02-06       Impact factor: 6.166

7.  Nanoparticle delivery of pooled siRNA for effective treatment of non-small cell lung cancer.

Authors:  Yang Yang; Yunxia Hu; Yuhua Wang; Jun Li; Feng Liu; Leaf Huang
Journal:  Mol Pharm       Date:  2012-06-22       Impact factor: 4.939

Review 8.  MYC as a regulator of ribosome biogenesis and protein synthesis.

Authors:  Jan van Riggelen; Alper Yetil; Dean W Felsher
Journal:  Nat Rev Cancer       Date:  2010-04       Impact factor: 60.716

9.  BNIP3L-dependent mitophagy accounts for mitochondrial clearance during 3 factors-induced somatic cell reprogramming.

Authors:  Ge Xiang; Liang Yang; Qi Long; Keshi Chen; Haite Tang; Yi Wu; Zihuang Liu; Yanshuang Zhou; Juntao Qi; Lingjun Zheng; Wenbo Liu; Zhongfu Ying; Weimin Fan; Hongyan Shi; Hongmei Li; Xiaobing Lin; Mi Gao; Jinglei Liu; Feixiang Bao; Linpeng Li; Lifan Duan; Min Li; Xingguo Liu
Journal:  Autophagy       Date:  2017-07-19       Impact factor: 16.016

10.  Synthetic molecules for disruption of the MYC protein-protein interface.

Authors:  Nicholas T Jacob; Pedro O Miranda; Ryan J Shirey; Ritika Gautam; Bin Zhou; M Elena de Orbe Izquierdo; Mark S Hixon; Jonathan R Hart; Lynn Ueno; Peter K Vogt; Kim D Janda
Journal:  Bioorg Med Chem       Date:  2018-07-11       Impact factor: 3.641
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