Literature DB >> 16061334

Synthesis and transdermal penetration of NSAID glycoside esters.

Henk Swart1, Jaco C Breytenbach, Jonathan Hadgraft, Jeanetta du Plessis.   

Abstract

The glucoside and mannoside derivatives of the NSAIDs flurbiprofen, ibuprofen, ketoprofen and naproxen were synthesised and their penetration through human skin was determined. Experimental transdermal flux data showed that the parent NSAIDs penetrated human skin to a much higher extent than the glycosides.

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Year:  2005        PMID: 16061334     DOI: 10.1016/j.ijpharm.2005.05.030

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


  4 in total

1.  A Data-Mining Approach for the Quantitative Assessment of Physicochemical Properties of Molecular Compounds in the Skin Flux.

Authors:  Hoo-Kyun Choi; Gayathri Acharya; Yugyung Lee; Chi H Lee
Journal:  AAPS PharmSciTech       Date:  2021-03-25       Impact factor: 3.246

2.  Ester prodrug-loaded electrospun cellulose acetate fiber mats as transdermal drug delivery systems.

Authors:  Xiao-mei Wu; Christopher J Branford-White; Li-min Zhu; Nichoals P Chatterton; Deng-guang Yu
Journal:  J Mater Sci Mater Med       Date:  2010-05-25       Impact factor: 3.896

Review 3.  Design for optimized topical delivery: Prodrugs and a paradigm change.

Authors:  Kenneth B Sloan; Scott C Wasdo; Jarkko Rautio
Journal:  Pharm Res       Date:  2006-11-16       Impact factor: 4.580

4.  A novel murine model for the in vivo study of transdermal drug penetration.

Authors:  Gábor Eros; Petra Hartmann; Szilvia Berkó; Eszter Csizmazia; Erzsébet Csányi; Anita Sztojkov-Ivanov; István Németh; Piroska Szabó-Révész; István Zupkó; Lajos Kemény
Journal:  ScientificWorldJournal       Date:  2012-01-04
  4 in total

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