Literature DB >> 16059580

[Ocular toxicity caused by chloroquine: case report].

Eliane Terumi Inada1, Karina Paula Watanabe, Sérgio Gustavo Tanaka, Luís Antônio Sakakisbara.   

Abstract

To report a case of ocular toxicity due to chloroquine. The best visual acuity was measured in both eyes with the Snellen chart. Slit-lamp examination of anterior segment, refraction, dilated fundus examination, fluorescein angiography and retinography was done in a 53-year-old patient, female, with rheumatoid arthritis. She had used chloroquine during 6 years and had stopped for 1 year when she came to our service. She had best corrected visual acuity of 20/200 and 20/40. Slit-lamp examination showed intraocular lens in right eye and nuclear cataract (1+/4) in the other, and bilateral corneal subepithelial opacity inferior to the visual axis. Fundus examination showed macular area with retinal pigment epithelium atrophy. Fluorescein angiography showed a bull's eye maculopathy. Report of a typical keratopathy and maculopathy caused by chloroquine.

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Year:  2005        PMID: 16059580     DOI: 10.1590/s0004-27492005000300027

Source DB:  PubMed          Journal:  Arq Bras Oftalmol        ISSN: 0004-2749            Impact factor:   0.872


  2 in total

Review 1.  Age-related cataracts: Role of unfolded protein response, Ca2+ mobilization, epigenetic DNA modifications, and loss of Nrf2/Keap1 dependent cytoprotection.

Authors:  Palsamy Periyasamy; Toshimichi Shinohara
Journal:  Prog Retin Eye Res       Date:  2017-08-31       Impact factor: 21.198

2.  Chloroquine-induced bull's eye maculopathy in rheumatoid arthritis: related to disease duration?

Authors:  Samuel K Shinjo; Otacílio O Maia; Vivian A P Tizziani; Celso Morita; Jussara A L Kochen; Walter Y Takahashi; Ieda M M Laurindo
Journal:  Clin Rheumatol       Date:  2007-01-31       Impact factor: 3.650

  2 in total

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