Literature DB >> 16059448

SV2A: more than just a new target for AEDs.

Asla Pitkänen.   

Abstract

Entities:  

Year:  2005        PMID: 16059448      PMCID: PMC1176320          DOI: 10.1111/j.1535-7597.2005.05104.x

Source DB:  PubMed          Journal:  Epilepsy Curr        ISSN: 1535-7511            Impact factor:   7.500


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  10 in total

1.  SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release.

Authors:  R Janz; Y Goda; M Geppert; M Missler; T C Südhof
Journal:  Neuron       Date:  1999-12       Impact factor: 17.173

2.  Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A).

Authors:  K M Crowder; J M Gunther; T A Jones; B D Hale; H Z Zhang; M R Peterson; R H Scheller; C Chavkin; S M Bajjalieh
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-21       Impact factor: 11.205

3.  SV2 modulates the size of the readily releasable pool of secretory vesicles.

Authors:  T Xu; S M Bajjalieh
Journal:  Nat Cell Biol       Date:  2001-08       Impact factor: 28.824

4.  Antiepileptogenic effects of the novel anticonvulsant levetiracetam (ucb L059) in the kindling model of temporal lobe epilepsy.

Authors:  W Löscher; D Hönack; C Rundfeldt
Journal:  J Pharmacol Exp Ther       Date:  1998-02       Impact factor: 4.030

5.  Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy.

Authors:  H Klitgaard; A Matagne; J Gobert; E Wülfert
Journal:  Eur J Pharmacol       Date:  1998-07-24       Impact factor: 4.432

6.  Localization and photoaffinity labelling of the levetiracetam binding site in rat brain and certain cell lines.

Authors:  Bruno Fuks; Michel Gillard; Philippe Michel; Berkley Lynch; Pascale Vertongen; Pierre Leprince; Henrik Klitgaard; Pierre Chatelain
Journal:  Eur J Pharmacol       Date:  2003-09-30       Impact factor: 4.432

7.  The antiepileptic drug levetiracetam selectively modifies kindling-induced alterations in gene expression in the temporal lobe of rats.

Authors:  Jessie Gu; Berkley A Lynch; Dina Anderson; Henrik Klitgaard; Sun Lu; Michael Elashoff; Ulrich Ebert; Heidrun Potschka; Wolfgang Löscher
Journal:  Eur J Neurosci       Date:  2004-01       Impact factor: 3.386

8.  Accumulation of 7S SNARE complexes in hippocampal synaptosomes from chronically kindled rats.

Authors:  E A Matveeva; S W Whiteheart; J T Slevin
Journal:  J Neurochem       Date:  2003-02       Impact factor: 5.372

9.  The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes.

Authors:  M Noyer; M Gillard; A Matagne; J P Hénichart; E Wülfert
Journal:  Eur J Pharmacol       Date:  1995-11-14       Impact factor: 4.432

10.  The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam.

Authors:  Berkley A Lynch; Nathalie Lambeng; Karl Nocka; Patricia Kensel-Hammes; Sandra M Bajjalieh; Alain Matagne; Bruno Fuks
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-21       Impact factor: 11.205

  10 in total

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