Literature DB >> 1605936

[Change in congener analysis caused by percutaneous absorption of propanol-containing antiseptics].

O Peschel1, M F Bauer, T Gilg, L V Meyer, L von Meyer.   

Abstract

According to the forensic literature, an alteration of blood alcohol concentration through alcohol disinfection before venepuncture is unlikely, however, percutaneous resorption of alcohol containing antiseptics is well documented. There are no investigations available, elucidating to what extent this is also correct for congener alcohols, particularly propanol-1/-2, which have serum levels in range of mg/l. In experiments with surgical hand and local skin disinfection, carried out with and without oral alcohol, relevant levels of propanol-1/-2 between 0.2 and 2 mg/l were measured. We conclude, that the routine clinical use of antiseptics is able to alterate and to falsify congener levels and can lead to incorrect interpretation of congener analysis.

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Year:  1992        PMID: 1605936

Source DB:  PubMed          Journal:  Blutalkohol        ISSN: 0006-5250


  4 in total

1.  Transdermal absorption of ethanol- and 1-propanol-containing hand disinfectants.

Authors:  Reinhold Andreas Lang; Dianne Egli-Gany; Florian Holger Hubert Brill; Johannes Georg Böttrich; Marion Breuer; Burkhard Breuer; Martin Hartwig Kirschner
Journal:  Langenbecks Arch Surg       Date:  2010-12-01       Impact factor: 3.445

Review 2.  Ethanol is indispensable for virucidal hand antisepsis: memorandum from the alcohol-based hand rub (ABHR) Task Force, WHO Collaborating Centre on Patient Safety, and the Commission for Hospital Hygiene and Infection Prevention (KRINKO), Robert Koch Institute, Berlin, Germany.

Authors:  Axel Kramer; Mardjan Arvand; Bärbel Christiansen; Stephanie Dancer; Maren Eggers; Martin Exner; Dieter Müller; Nico T Mutters; Ingeborg Schwebke; Didier Pittet
Journal:  Antimicrob Resist Infect Control       Date:  2022-07-06       Impact factor: 6.454

3.  Transdermal resorption of an ethanol- and 2-propanol-containing skin disinfectant.

Authors:  Martin Hartwig Kirschner; Reinhold Andreas Lang; Burkhard Breuer; Marion Breuer; Corinna Schulze Gronover; Thomas Zwingers; Johannes Georg Böttrich; Andreas Arndt; Ute Brauer; Matthias Hintzpeter; Marc-Alexander Burmeister; Jan-Dirk Fauteck
Journal:  Langenbecks Arch Surg       Date:  2007-11-08       Impact factor: 3.445

Review 4.  Alcohol congener analysis and the source of alcohol: a review.

Authors:  Luke N Rodda; Jochen Beyer; Dimitri Gerostamoulos; Olaf H Drummer
Journal:  Forensic Sci Med Pathol       Date:  2013-03-03       Impact factor: 2.007

  4 in total

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