Literature DB >> 1605678

Numerical chromosome anomalies after fertilization of freeze-thawed mouse oocytes.

K Sterzik1, B Rosenbusch, D Grab, A Wahl, H M Beier, C Lauritzen.   

Abstract

The chromosome complement of first cleavage stage mouse embryos was analyzed to investigate the effect of slow freezing-fast thawing cryopreservation on chromosome numbers by comparing these numbers with those found fresh after fertilization of control oocytes. Fewer frozen-thawed (34.1%) than control oocytes (75.0%) cleaved to the 2-cell stage after in vitro fertilization. The incidence of hyperploidy was significantly increased by freezing (4.5% vs. 0% in controls). Polyploidy was not significantly affected (17.0% for freeze-thaw embryos vs. 26.2% for controls).

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Year:  1992        PMID: 1605678     DOI: 10.1007/bf02718375

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  18 in total

1.  The effect of PMSG dose on the incidence of chromosomal anomalies in mouse embryos fertilized in vitro.

Authors:  I Maudlin; L R Fraser
Journal:  J Reprod Fertil       Date:  1977-07

2.  Increase in digyny explains polyploidy after in-vitro fertilization of frozen-thawed mouse oocytes.

Authors:  J Carroll; G M Warnes; C D Matthews
Journal:  J Reprod Fertil       Date:  1989-03

3.  Ultrarapid freezing: a new low-cost and effective method of embryo cryopreservation.

Authors:  A Trounson; A Peura; C Kirby
Journal:  Fertil Steril       Date:  1987-11       Impact factor: 7.329

4.  The chromosome complement of first-cleavage mouse embryos after in vitro fertilization.

Authors:  J Santaló; A M Estop; J Egozcue
Journal:  J In Vitro Fert Embryo Transf       Date:  1986-04

5.  Vitrification of mouse oocytes results in aneuploid zygotes and malformed fetuses.

Authors:  I Kola; C Kirby; J Shaw; A Davey; A Trounson
Journal:  Teratology       Date:  1988-11

6.  Birth after cryopreservation of unfertilized oocytes.

Authors:  J F van Uem; E R Siebzehnrübl; B Schuh; R Koch; S Trotnow; N Lang
Journal:  Lancet       Date:  1987-03-28       Impact factor: 79.321

7.  Human embryo features that influence the success of cryopreservation with the use of 1,2 propanediol.

Authors:  B Lassalle; J Testart; J P Renard
Journal:  Fertil Steril       Date:  1985-11       Impact factor: 7.329

8.  Effect of 1,2-propanediol and dimethylsulphoxide on the meiotic spindle of the mouse oocyte.

Authors:  J Van der Elst; E Van den Abbeel; R Jacobs; E Wisse; A Van Steirteghem
Journal:  Hum Reprod       Date:  1988-11       Impact factor: 6.918

9.  Analysis of aneuploidy in first-cleavage mouse embryos fertilized in vitro and in vivo.

Authors:  L R Fraser; I Maudlin
Journal:  Environ Health Perspect       Date:  1979-08       Impact factor: 9.031

10.  The effect of dimethylsulphoxide on the microtubular system of the mouse oocyte.

Authors:  M H Johnson; S J Pickering
Journal:  Development       Date:  1987-06       Impact factor: 6.868

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