| Literature DB >> 1605678 |
K Sterzik1, B Rosenbusch, D Grab, A Wahl, H M Beier, C Lauritzen.
Abstract
The chromosome complement of first cleavage stage mouse embryos was analyzed to investigate the effect of slow freezing-fast thawing cryopreservation on chromosome numbers by comparing these numbers with those found fresh after fertilization of control oocytes. Fewer frozen-thawed (34.1%) than control oocytes (75.0%) cleaved to the 2-cell stage after in vitro fertilization. The incidence of hyperploidy was significantly increased by freezing (4.5% vs. 0% in controls). Polyploidy was not significantly affected (17.0% for freeze-thaw embryos vs. 26.2% for controls).Entities:
Mesh:
Year: 1992 PMID: 1605678 DOI: 10.1007/bf02718375
Source DB: PubMed Journal: Arch Gynecol Obstet ISSN: 0932-0067 Impact factor: 2.344