BACKGROUND: Studies have linked asthma death to either increased or decreased use of medical services. METHODS: A population based case-control study of asthma deaths in 1994-8 was performed in 22 English, six Scottish, and five Welsh health authorities/boards. All 681 subjects who died were under the age of 65 years with asthma in Part I on the death certificates. After exclusions, 532 hospital controls were matched to 532 cases for age, district, and date of asthma admission/death. Data were extracted blind from primary care records. RESULTS: The median age of the subjects who died was 53 years; 60% of cases and 64% of controls were female. There was little difference in outpatient attendance (55% and 55%), hospital admission for asthma (51% and 54%), and median inpatient days (20 days and 15 days) in the previous 5 years. After mutual adjustment and adjustment for sex, using conditional logistic regression, three variables were independently associated with asthma death: fewer general practice contacts (odds ratio 0.82 (95% confidence interval (CI) 0.74 to 0.91) per 5 contacts) in the previous year, more home visits (1.14 (95% CI 1.08 to 1.21) per visit) in the previous year, and fewer peak expiratory flow recordings (0.83 (95% CI 0.74 to 0.92) per occasion) in the previous 3 months. These associations were similar after adjustment for markers of severity, psychosocial factors, systemic steroids, short acting bronchodilators and antibiotics, although the association with peak flow was weakened and just lost significance. CONCLUSION: Asthma death is associated with less use of primary care services. Both practice and patient factors may be involved and a better understanding of these may offer possibilities for reducing asthma death.
BACKGROUND: Studies have linked asthma death to either increased or decreased use of medical services. METHODS: A population based case-control study of asthma deaths in 1994-8 was performed in 22 English, six Scottish, and five Welsh health authorities/boards. All 681 subjects who died were under the age of 65 years with asthma in Part I on the death certificates. After exclusions, 532 hospital controls were matched to 532 cases for age, district, and date of asthma admission/death. Data were extracted blind from primary care records. RESULTS: The median age of the subjects who died was 53 years; 60% of cases and 64% of controls were female. There was little difference in outpatient attendance (55% and 55%), hospital admission for asthma (51% and 54%), and median inpatient days (20 days and 15 days) in the previous 5 years. After mutual adjustment and adjustment for sex, using conditional logistic regression, three variables were independently associated with asthma death: fewer general practice contacts (odds ratio 0.82 (95% confidence interval (CI) 0.74 to 0.91) per 5 contacts) in the previous year, more home visits (1.14 (95% CI 1.08 to 1.21) per visit) in the previous year, and fewer peak expiratory flow recordings (0.83 (95% CI 0.74 to 0.92) per occasion) in the previous 3 months. These associations were similar after adjustment for markers of severity, psychosocial factors, systemic steroids, short acting bronchodilators and antibiotics, although the association with peak flow was weakened and just lost significance. CONCLUSION:Asthma death is associated with less use of primary care services. Both practice and patient factors may be involved and a better understanding of these may offer possibilities for reducing asthma death.
Authors: Shawn D Aaron; Katherine L Vandemheen; Wendy Ferris; Dean Fergusson; Elizabeth Tullis; David Haase; Yves Berthiaume; Neil Brown; Pearce Wilcox; Veronica Yozghatlian; Peter Bye; Scott Bell; Francis Chan; Barbara Rose; Alphonse Jeanneret; Anne Stephenson; Mary Noseworthy; Andreas Freitag; Nigel Paterson; Steve Doucette; Colin Harbour; Michel Ruel; Noni MacDonald Journal: Lancet Date: 2005 Aug 6-12 Impact factor: 79.321
Authors: P M Sturdy; C R Victor; H R Anderson; J M Bland; B K Butland; B D W Harrison; C Peckitt; J C Taylor Journal: Thorax Date: 2002-12 Impact factor: 9.139
Authors: D A Campbell; G McLennan; J R Coates; P A Frith; P A Gluyas; K M Latimer; C G Luke; A J Martin; D M Roder; R E Ruffin Journal: Eur Respir J Date: 1994-03 Impact factor: 16.671
Authors: Jieqiong Freda Yang; Rekha Chaudhuri; Neil C Thomson; Nitish Ramparsad; Hugh O'Pray; Stephen Barclay; Sean MacBride-Stewart; Craig McCallum; Varun Sharma; Charles McSharry; Dianne Murray; Malcolm Shepherd; Wai-Ting Nicola Lee Journal: NPJ Prim Care Respir Med Date: 2018-09-19 Impact factor: 2.871
Authors: Jane R Smith; Stanley Musgrave; Estelle Payerne; Michael Noble; Erika J Sims; Allan B Clark; Garry Barton; Hilary Pinnock; Aziz Sheikh; Andrew M Wilson Journal: Trials Date: 2018-08-29 Impact factor: 2.279