Literature DB >> 16054094

When pouring water on the fire makes it burn brighter.

Alan M Fogelman.   

Abstract

Earlier work seems to suggest that overexpression of uncoupling protein 1 would be anti-inflammatory. However, new findings show that expression of uncoupling protein 1 in aortic smooth muscle cells of mice increases reactive oxygen species, activates the renin-angiotensin system, elevates blood pressure, and worsens atherosclerosis.

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Year:  2005        PMID： 16054094     DOI： 10.1016/j.cmet.2005.06.009

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  4 in total

Review 1.  Multiple indications for anti-inflammatory apolipoprotein mimetic peptides.

Authors:  Brian J Van Lenten; Mohamad Navab; G M Anantharamaiah; Georgette M Buga; Srinivasa T Reddy; Alan M Fogelman
Journal:  Curr Opin Investig Drugs       Date:  2008-11

Review 2.  Proatherogenic high-density lipoprotein, vascular inflammation, and mimetic peptides.

Authors:  Roger Yu; Babak Yekta; Ladan Vakili; Navid Gharavi; Mohamad Navab; Daniel Marelli; Abbas Ardehali
Journal:  Curr Atheroscler Rep       Date:  2008-04       Impact factor: 5.113

Review 3.  The effect of apolipoprotein mimetic peptides in inflammatory disorders other than atherosclerosis.

Authors:  Mohamad Navab; G M Anantharamaiah; Alan M Fogelman
Journal:  Trends Cardiovasc Med       Date:  2008-02       Impact factor: 6.677

4.  Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients.

Authors:  Leanne T Bloedon; Richard Dunbar; Danielle Duffy; Paula Pinell-Salles; Robert Norris; Bruce J DeGroot; Rajesh Movva; Mohamad Navab; Alan M Fogelman; Daniel J Rader
Journal:  J Lipid Res       Date:  2008-03-06       Impact factor: 5.922
  4 in total

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