| Literature DB >> 16054057 |
Abstract
Ferroportin is the sole cellular efflux channel for iron and is regulated by the iron regulatory hormone hepcidin, which binds ferroportin and induces its internalization and degradation. New studies of ferroportin knockout mice define a key role for this transporter in physiological iron balance.Entities:
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Year: 2005 PMID： 16054057 DOI： 10.1016/j.cmet.2005.02.005
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287