| Literature DB >> 1605191 |
A J Verkerk1, B H Eussen, J O Van Hemel, B A Oostra.
Abstract
Cosmids, isolated from a 475 kb YAC that spans the fragile X region, and the YAC itself, were used for fluorescence in situ hybridization (FISH) on metaphase chromosomes from fragile X patients. Cosmid 22.3, containing most of the hybrid translocation breakpoints, shows in situ hybridization signals distal and proximal from the fragile X site. We propose that the size of the fragile site is limited to 20 kb.Entities:
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Year: 1992 PMID： 1605191 DOI： 10.1002/ajmg.1320430131
Source DB: PubMed Journal: Am J Med Genet ISSN： 0148-7299