| Literature DB >> 16051166 |
Joachim Weischenfeldt1, Jens Lykke-Andersen, Bo Porse.
Abstract
Messenger RNA transcripts that contain premature stop codons are degraded by a process termed nonsense-mediated mRNA decay (NMD). Although previously thought of as a pathway that rids the cell of non-functional mRNAs arising from mutations and processing errors, new research suggests a more general and evolutionarily important role for NMD in the control of gene expression.Mesh:
Substances:
Year: 2005 PMID: 16051166 DOI: 10.1016/j.cub.2005.07.002
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834