Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 First stereoselective syntheses of (-)-siphonodiol and (-)-tetrahydrosiphonodiol, bioactive polyacetylenes from marine sponges.

Literature DB >> 16050696

First stereoselective syntheses of (-)-siphonodiol and (-)-tetrahydrosiphonodiol, bioactive polyacetylenes from marine sponges.

Susana López¹, Francisco Fernández-Trillo, Pilar Midón, Luis Castedo, Carlos Saá.

Abstract

The first stereoselective total syntheses of the bioactive marine polyacetylenes (-)-siphonodiol and (-)-tetrahydrosiphonodiol were achieved using highly convergent approaches based on optimized Cadiot-Chodkiewicz and sequential Sonogashira cross-coupling reactions.

Entities: Chemical

Mesh：

Substances：

Year: 2005 PMID： 16050696 DOI： 10.1021/jo050807f

Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354

Keyword Cloud
Cited

6 in total

1. Organic chemistry: No double bond left behind.

Authors: David Sarlah
Journal: Nature Date: 2016-03-24 Impact factor: 49.962

2. A Short Synthesis of (S)-(+)-Siphonodiol.

Authors: Benjamin W Gung; Derek T Craft; Jessica Truelove
Journal: Tetrahedron Asymmetry Date: 2007-06-22

3. Polyacetylene diols with antiproliferative and driving Th1 polarization effects from the marine sponge Callyspongia sp.

Authors: Akemi Umeyama; Nanae Matsuoka; Rieko Mine; Akemi Nakata; Eri Arimoto; Miwa Matsui; Noboru Shoji; Shigenobu Arihara; Masao Takei; Toshihiro Hashimoto
Journal: J Nat Med Date: 2009-10-03 Impact factor: 2.343

First stereoselective syntheses of (-)-siphonodiol and (-)-tetrahydrosiphonodiol, bioactive polyacetylenes from marine sponges.

1. Organic chemistry: No double bond left behind.

2. A Short Synthesis of (S)-(+)-Siphonodiol.

3. Polyacetylene diols with antiproliferative and driving Th1 polarization effects from the marine sponge Callyspongia sp.

4. Sponge chemical defenses are a possible mechanism for increasing sponge abundance on reefs in Zanzibar.

5. Direct synthesis of Z-alkenyl halides through catalytic cross-metathesis.

Review 6. Metabolities from Marine Sponges of the Genus Callyspongia: Occurrence, Biological Activity, and NMR Data.