Literature DB >> 1604986

Preservation of hearing in bilateral acoustic neurinomas by deliberate partial resection.

M E Wigand1, T Haid, W Goertzen, S Wolf.   

Abstract

With the aim of preserving hearing, 20 acoustic neurinomas in 17 patients with neurofibromatosis 2 were intentionally submitted to an incomplete (80%) tumour removal. In 12 cases this was an operation on the last hearing ear with total deafness of the contralateral ear. If an auditus existed in both ears the better hearing ear was selected for the primary intervention. Early audiological controls evidenced residual hearing in 19 of the 20 cases operated on by the enlarged middle fossa approach, which was utilized inspite of the tumour diameters being between 1 and 6 cm in the cerebello-pontine angle. The oncologic and functional follow-up over 1 to 7 years showed different patterns of slow progression of hearing loss and of persistent auditory function over 2 to 7 years. Facial nerve function was excellent in 16 of the 18 controlled cases. Continued CT or MRT imaging revealed no signaling in 2 cases, constant tumour sizes in 10 cases and slow progression in 3 cases. With regard to the importance of an auditory communication in the younger adult, the described treatment modality appears to be the first choice method.

Entities:  

Mesh:

Year:  1992        PMID: 1604986     DOI: 10.1080/00016489.1992.11665411

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN: 0001-6489            Impact factor:   1.494


  2 in total

1.  Impact of Surgery on Long-Term Results of Hearing in Neurofibromatosis Type-2 Associated Vestibular Schwannomas.

Authors:  Isabel Gugel; Florian Grimm; Marina Liebsch; Julian Zipfel; Christian Teuber; Lan Kluwe; Victor-Felix Mautner; Marcos Tatagiba; Martin Ulrich Schuhmann
Journal:  Cancers (Basel)       Date:  2019-09-16       Impact factor: 6.639

2.  Managing NF2-associated vestibular schwannomas in children and young adults: review of an institutional series regarding effects of surgery and bevacizumab on growth rates, tumor volume, and hearing quality.

Authors:  Isabel Gugel; Julian Zipfel; Philip Hartjen; Lan Kluwe; Marcos Tatagiba; Victor-Felix Mautner; Martin Ulrich Schuhmann
Journal:  Childs Nerv Syst       Date:  2020-06-16       Impact factor: 1.475

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.