Literature DB >> 16048981

Nystatin induces secretion of interleukin (IL)-1beta, IL-8, and tumor necrosis factor alpha by a toll-like receptor-dependent mechanism.

Raymund R Razonable1, Martin Henault, Harold L Watson, Carlos V Paya.   

Abstract

Nystatin is an antifungal compound with potent proinflammatory properties. Herein, we demonstrate that nystatin induces interleukin (IL)-1beta, IL-8, and tumor necrosis factor alpha secretion through its activation of toll-like receptor 1 (TLR1) and TLR2. Hence, a TLR-dependent mechanism could serve as the molecular basis for the proinflammatory properties of nystatin.

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Year:  2005        PMID： 16048981      PMCID： PMC1196261          DOI： 10.1128/AAC.49.8.3546-3549.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  20 in total

1.  Liposomal nystatin against experimental pulmonary aspergillosis in persistently neutropenic rabbits: efficacy, safety and non-compartmental pharmacokinetics.

Authors:  A H Groll; C E Gonzalez; N Giri; K Kligys; W Love; J Peter; E Feuerstein; J Bacher; S C Piscitelli; T J Walsh
Journal:  J Antimicrob Chemother       Date:  1999-01       Impact factor: 5.790

2.  Two antifungal agents produced by a soil actinomycete.

Authors:  E L HAZEN; R BROWN
Journal:  Science       Date:  1950-10-13       Impact factor: 47.728

3.  Safety and efficacy of multilamellar liposomal nystatin against disseminated candidiasis in persistently neutropenic rabbits.

Authors:  A H Groll; V Petraitis; R Petraitiene; A Field-Ridley; M Calendario; J Bacher; S C Piscitelli; T J Walsh
Journal:  Antimicrob Agents Chemother       Date:  1999-10       Impact factor: 5.191

4.  Secretion of proinflammatory cytokines and chemokines during amphotericin B exposure is mediated by coactivation of toll-like receptors 1 and 2.

Authors:  Raymund R Razonable; Martin Henault; Linda N Lee; Carmen Laethem; Paul A Johnston; Harold L Watson; Carlos V Paya
Journal:  Antimicrob Agents Chemother       Date:  2005-04       Impact factor: 5.191

Review 5.  Progress in antimycotic chemotherapy 1945-1980.

Authors:  R J Holt
Journal:  Infection       Date:  1980       Impact factor: 3.553

6.  Chemical diversity of polyene macrolides produced by Streptomyces noursei ATCC 11455 and recombinant strain ERD44 with genetically altered polyketide synthase NysC.

Authors:  Per Bruheim; Sven E F Borgos; Pascale Tsan; Håvard Sletta; Trond E Ellingsen; Jean-Marc Lancelin; Sergey B Zotchev
Journal:  Antimicrob Agents Chemother       Date:  2004-11       Impact factor: 5.191

7.  Activity of liposomal nystatin against disseminated Aspergillus fumigatus infection in neutropenic mice.

Authors:  T L Wallace; V Paetznick; P A Cossum; G Lopez-Berestein; J H Rex; E Anaissie
Journal:  Antimicrob Agents Chemother       Date:  1997-10       Impact factor: 5.191

8.  Anti-inflammatory activity of Arnica montana 6cH: preclinical study in animals.

Authors:  S B Macêdo; L R Ferreira; F F Perazzo; J C Carvalho
Journal:  Homeopathy       Date:  2004-04       Impact factor: 1.444

9.  Toxicity and therapeutic effects in mice of liposome-encapsulated nystatin for systemic fungal infections.

Authors:  R T Mehta; R L Hopfer; T McQueen; R L Juliano; G Lopez-Berestein
Journal:  Antimicrob Agents Chemother       Date:  1987-12       Impact factor: 5.191

Review 10.  Toll-like receptors and their signaling mechanisms.

Authors:  Shizuo Akira; Shintaro Sato
Journal:  Scand J Infect Dis       Date:  2003
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  11 in total

1.  TLR9 and MyD88 are crucial for the maturation and activation of dendritic cells by paromomycin-miltefosine combination therapy in visceral leishmaniasis.

Authors:  Sushmita Das; Mukta Rani; Vidyanand Rabidas; Krishna Pandey; Ganesh Chandra Sahoo; Pradeep Das
Journal:  Br J Pharmacol       Date:  2014-03       Impact factor: 8.739

2.  Cysteine Oxidation Targets Peroxiredoxins 1 and 2 for Exosomal Release through a Novel Mechanism of Redox-Dependent Secretion.

Authors:  Lisa Mullen; Eva-Maria Hanschmann; Christopher Horst Lillig; Leonore A Herzenberg; Pietro Ghezzi
Journal:  Mol Med       Date:  2015-02-13       Impact factor: 6.354

3.  Modelling dysregulated Na+ absorption in airway epithelial cells with mucosal nystatin treatment.

Authors:  Alessandra Livraghi; Marcus Mall; Anthony M Paradiso; Richard C Boucher; Carla M Pedrosa Ribeiro
Journal:  Am J Respir Cell Mol Biol       Date:  2007-11-07       Impact factor: 6.914

4.  Effect of Danshen aqueous extract on serum hs-CRP, IL-8, IL-10, TNF-α levels, and IL-10 mRNA, TNF-α mRNA expression levels, cerebral TGF-β1 positive expression level and its neuroprotective mechanisms in CIR rats.

Authors:  Xue-Yun Liang; Hai-Ning Li; Xiao-Yan Yang; Wen-Yan Zhou; Jian-Guo Niu; Ben-Dong Chen
Journal:  Mol Biol Rep       Date:  2013-02-02       Impact factor: 2.316

5.  R753Q single-nucleotide polymorphism impairs toll-like receptor 2 recognition of hepatitis C virus core and nonstructural 3 proteins.

Authors:  Robert A Brown; Jonathon H Gralewski; Albert J Eid; Bettina M Knoll; Robert W Finberg; Raymund R Razonable
Journal:  Transplantation       Date:  2010-04-15       Impact factor: 4.939

Review 6.  Beyond muscles: The untapped potential of creatine.

Authors:  Lisa A Riesberg; Stephanie A Weed; Thomas L McDonald; Joan M Eckerson; Kristen M Drescher
Journal:  Int Immunopharmacol       Date:  2016-01-08       Impact factor: 4.932

Review 7.  Learning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines.

Authors:  Jesper Melchjorsen
Journal:  Viruses       Date:  2013-01-31       Impact factor: 5.048

8.  Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome.

Authors:  Murthy Narayana Darisipudi; Ramanjaneyulu Allam; Khader Valli Rupanagudi; Hans-Joachim Anders
Journal:  PLoS One       Date:  2011-05-23       Impact factor: 3.240

9.  A Novel High Performance Liquid Chromatographic Method for Determination of Nystatin in Pharmaceutical Formulations by Box-Behnken Statistical Experiment Design.

Authors:  Farnaz Shokraneh; Ramin Asgharian; Assem Abdollahpour; Mehdi Ramin; Ali Montaseri; Arash Mahboubi
Journal:  Iran J Pharm Res       Date:  2015       Impact factor: 1.696

10.  Milk matters: soluble Toll-like receptor 2 (sTLR2) in breast milk significantly inhibits HIV-1 infection and inflammation.

Authors:  Bethany M Henrick; Kakon Nag; Xiao-Dan Yao; Anna G Drannik; Grace M Aldrovandi; Kenneth L Rosenthal
Journal:  PLoS One       Date:  2012-07-06       Impact factor: 3.240
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