Literature DB >> 16048975

Therapeutic effect of ME1036 on endocarditis experimentally induced by methicillin-resistant Staphylococcus aureus.

Jun Nagura1, Koji Kijima, Mizuyo Kurazono, Sho Takahata, Toshie Sugano, Yukari Tanaka, Yoko Hirai, Keiko Yamada, Yoshihiro Takayama, Eiki Shitara, Minoru Yonezawa.   

Abstract

The efficacy of ME1036, a novel parenteral carbapenem, was compared with that of vancomycin by using a rabbit model of methicillin-resistant Staphylococcus aureus (MRSA) endocarditis. Compared with vancomycin, ME1036 reduced the bacterial counts in the vegetations at a lower dosage or over a shorter period of administration when it was used for the treatment of MRSA endocarditis.

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Year:  2005        PMID： 16048975      PMCID： PMC1196270          DOI： 10.1128/AAC.49.8.3526-3528.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

Review 1.  Infective endocarditis in adults.

Authors:  E Mylonakis; S B Calderwood
Journal:  N Engl J Med       Date:  2001-11-01       Impact factor: 91.245

2.  ACC/AHA Guidelines for the Management of Patients With Valvular Heart Disease. Executive Summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients With Valvular Heart Disease).

Authors:  R O Bonow; B Carabello; A C de Leon; L H Edmunds; B J Fedderly; M D Freed; W H Gaasch; C R McKay; R A Nishimura; P T O'Gara; R A O'Rourke; S H Rahimtoola; J L Ritchie; M D Cheitlin; K A Eagle; T J Gardner; A Garson; R J Gibbons; R O Russell; T J Ryan; S C Smith
Journal:  J Heart Valve Dis       Date:  1998-11

3.  Experimental bacterial endocarditis. I. Colonization of a sterile vegetation.

Authors:  D T Durack; P B Beeson
Journal:  Br J Exp Pathol       Date:  1972-02

Review 4.  Epidemiology of methicillin-resistant staphylococci in Europe.

Authors:  S Stefani; P E Varaldo
Journal:  Clin Microbiol Infect       Date:  2003-12       Impact factor: 8.067

5.  Vancomycin therapy for methicillin-resistant Staphylococcus aureus.

Authors:  T C Sorrell; D R Packham; S Shanker; M Foldes; R Munro
Journal:  Ann Intern Med       Date:  1982-09       Impact factor: 25.391

6.  In vitro activities of ME1036 (CP5609), a novel parenteral carbapenem, against methicillin-resistant staphylococci.

Authors:  Mizuyo Kurazono; Takashi Ida; Keiko Yamada; Yoko Hirai; Takahisa Maruyama; Eiki Shitara; Minoru Yonezawa
Journal:  Antimicrob Agents Chemother       Date:  2004-08       Impact factor: 5.191

Review 7.  Infective endocarditis: review of 135 cases over 9 years.

Authors:  R M Sandre; S D Shafran
Journal:  Clin Infect Dis       Date:  1996-02       Impact factor: 9.079

8.  Staphylococcus aureus bacteremia and endocarditis: the Grady Memorial Hospital experience with methicillin-sensitive S aureus and methicillin-resistant S aureus bacteremia.

Authors:  James Abraham; Craig Mansour; Emir Veledar; Bobby Khan; Stamatios Lerakis
Journal:  Am Heart J       Date:  2004-03       Impact factor: 4.749

9.  Experimental endocarditis. II. Staphylococcal infection of the aortic valve following placement of a polyethylene catheter in the left side of the heart.

Authors:  B B Perlman; L R Freedman
Journal:  Yale J Biol Med       Date:  1971-10
  9 in total
  1 in total

Review 1.  Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.

Authors:  Leticia I Llarrull; Jed F Fisher; Shahriar Mobashery
Journal:  Antimicrob Agents Chemother       Date:  2009-05-26       Impact factor: 5.191
  1 in total

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