Literature DB >> 16048332

A rapid synthesis of hexofuranose-like iminosugars using ring-closing metathesis.

Sylvaine Cren1, Claire Wilson, Neil R Thomas.   

Abstract

Two new 1-N-iminosugars have been prepared as hexofuranose analogues in an efficient manner by an RCM-based route. Both 3,4-disubstituted pyrrolidines display moderate inhibitory activity against Mycobacterium smegmatis galactan biosynthesis. [structure: see text]

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 16048332     DOI： 10.1021/ol051232b

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Synthesis of 1-deoxysphingosine derivatives with conformationally restricted pyrrolidinediol head groups.

Authors:  Ann M Dougherty; Frank E McDonald; Dennis C Liotta; Steven J Moody; David C Pallas; Carrie D Pack; Alfred H Merrill
Journal:  Org Lett       Date:  2006-02-16       Impact factor: 6.005

2.  Metathesis access to monocyclic iminocyclitol-based therapeutic agents.

Authors:  Ileana Dragutan; Valerian Dragutan; Carmen Mitan; Hermanus Cm Vosloo; Lionel Delaude; Albert Demonceau
Journal:  Beilstein J Org Chem       Date:  2011-05-27       Impact factor: 2.883

Review 3.  Biosynthesis of Galactan in Mycobacterium tuberculosis as a Viable TB Drug Target?

Authors:  Zuzana Konyariková; Karin Savková; Stanislav Kozmon; Katarína Mikušová
Journal:  Antibiotics (Basel)       Date:  2020-01-06
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.