Literature DB >> 16048329

Lewis base catalyzed ring opening of aziridines with silylated nucleophiles.

Satoshi Minakata1, Yuriko Okada, Yoji Oderaotoshi, Mitsuo Komatsu.   

Abstract

The ring opening of N-tosylaziridines with trimethylsilylated nucleophiles, catalyzed by N,N,N',N'-tetramethylethylenediamine, led to the production of beta-functionalized sulfonamides in good to excellent yields with high regioselectivity. [reaction: see text]

Entities:  

Year:  2005        PMID: 16048329     DOI: 10.1021/ol051186f

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

Review 1.  Organocatalyzed enantioselective desymmetrization of aziridines and epoxides.

Authors:  Ping-An Wang
Journal:  Beilstein J Org Chem       Date:  2013-08-15       Impact factor: 2.883

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.