| Literature DB >> 16048248 |
Peter J Margetts1, Kook-Hwan Oh, Martin Kolb.
Abstract
We have provided evidence from adenovirus-mediated gene transfer to the peritoneum that transforming growth factor-beta1 mimics many of the functional and structural changes in the peritoneum in patients on long-term peritoneal dialysis, including fibrosis, increased submesothelial thickness, angiogenesis, increased solute transport, and ultrafiltration dysfunction. We review several key properties of this important fibrogenic molecule.Entities:
Mesh:
Substances:
Year: 2005 PMID: 16048248
Source DB: PubMed Journal: Perit Dial Int ISSN: 0896-8608 Impact factor: 1.756