| Literature DB >> 16046130 |
Joseph Pontillo1, Zhiqiang Guo, Dongpei Wu, R Scott Struthers, Chen Chen.
Abstract
Several efficient synthetic routes for 2-, 4-, and 6-aryl-1,2,4-triazine-3,5-diones were developed. Derivatives were synthesized and studied as gonadotropin-releasing hormone antagonists in an effort to understand structure-activity relationships of the monocyclic compounds.Entities:
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Year: 2005 PMID： 16046130 DOI： 10.1016/j.bmcl.2005.06.057
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823