Literature DB >> 16044094

3,4-methylenedioxymethamphetamine (MDMA) intoxication in an infant chronically exposed to cocaine.

Oscar Garcia-Algar1, Nuria López, Mariona Bonet, Manuela Pellegrini, Emilia Marchei, Simona Pichini.   

Abstract

Accidental ingestion of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) was detected in an infant admitted at the Pediatric Emergency Department by drug testing in urine. Concentrations of MDMA and its principal metabolite 4-hydroxy-3-methoxymethamphetamine (HMMA) in the infant's hydrolyzed urine were 11.7 mg/L and 34.4 mg/L, respectively. Apparent febrile convulsions and cardiovascular side effects resolved within 1 day after treatment with benzodiazepines. Chronic exposure to cocaine was evidenced by segmental hair analysis. Continuous maternal denial of the presence of any drug in the household made diagnosis of accidental ingestion of MDMA and chronic exposure to cocaine problematic. Periodic clinical and laboratory follow-ups were requested to check eventual long-term effects of exposure to illicit drugs and discontinuation of the child from exposure to dangerous environments.

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Year:  2005        PMID: 16044094     DOI: 10.1097/01.ftd.0000166041.97524.50

Source DB:  PubMed          Journal:  Ther Drug Monit        ISSN: 0163-4356            Impact factor:   3.681


  7 in total

1.  Accidental ecstasy intoxication in an 8-month-old infant.

Authors:  Corien W E van Rijswijk; Martin C J Kneyber; Frans B Plötz
Journal:  Intensive Care Med       Date:  2006-01-27       Impact factor: 17.440

Review 2.  A developmental comparison of the neurobehavioral effects of ecstasy (MDMA).

Authors:  Brian J Piper
Journal:  Neurotoxicol Teratol       Date:  2006-10-20       Impact factor: 3.763

Review 3.  Ecstasy intoxication as an unusual cause of epileptic seizures in young children.

Authors:  Steven Pauwels; Francis Lemmens; Kim Eerdekens; Joris Penders; Koen Poesen; Koen Desmet; Pieter Vermeersch
Journal:  Eur J Pediatr       Date:  2013-07-05       Impact factor: 3.183

4.  Severe Ecstasy poisoning in an 8-month-old infant.

Authors:  Frank Eifinger; Bernhard Roth; Lars Kröner; Markus A Rothschild
Journal:  Eur J Pediatr       Date:  2007-09-26       Impact factor: 3.183

5.  Acute heroin intoxication in a baby chronically exposed to cocaine and heroin: a case report.

Authors:  Xavier Joya; Bibiana Fríguls; Marta Simó; Ester Civit; Rafael de la Torre; Antonio Palomeque; Oriol Vall; Simona Pichini; Oscar Garcia-Algar
Journal:  J Med Case Rep       Date:  2011-07-05

6.  Hair analysis following chronic smoked-drugs-of-abuse exposure in adults and their toddler: a case report.

Authors:  Esther Papaseit; Xavier Joya; Marta Velasco; Ester Civit; Pau Mota; Marta Bertran; Oriol Vall; Oscar Garcia-Algar
Journal:  J Med Case Rep       Date:  2011-12-10

7.  Assessment of unsuspected exposure to drugs of abuse in children from a Mediterranean city by hair testing.

Authors:  Simona Pichini; Oscar Garcia-Algar; Airam Alvarez; Massimo Gottardi; Emilia Marchei; Fiorenza Svaizer; Manuela Pellegrini; Maria Concetta Rotolo; Roberta Pacifici
Journal:  Int J Environ Res Public Health       Date:  2014-02-21       Impact factor: 3.390

  7 in total

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