| Literature DB >> 16043810 |
C DeGiorgio1, C Heck, S Bunch, J Britton, P Green, M Lancman, J Murphy, P Olejniczak, J Shih, S Arrambide, J Soss.
Abstract
Vagus nerve stimulation (VNS) is an effective adjunctive treatment for intractable epilepsy. However, the optimal range of device duty-cycles [on/(on + off times)] is poorly understood. The authors performed a multicenter, randomized trial of three unique modes of VNS, which varied primarily by duty-cycle. The results indicate that the three duty-cycles were equally effective. The data support the use of standard duty-cycles as initial therapy.Entities:
Mesh：
Year: 2005 PMID： 16043810 DOI： 10.1212/01.wnl.0000168899.11598.00
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910