Literature DB >> 16042355

Risk factors for androgen decline in older males: lifestyle, chronic diseases and drugs.

A M Isidori1, A Lenzi.   

Abstract

The aging process in men is accompanied by a progressive decline in serum testosterone levels. In addition to chronological aging, the various illnesses occurring in mid- to late-adult life and the medications used to treat them further contribute to lowering circulating testosterone levels. Any acute severe illness produces hypogonadotrophic hypogonadism; but also chronic illnesses, such as diabetes, cardiovascular disease and hypertension, lifestyle habits, such as tobacco and alcohol intake, and nutritional factors, from malnutrition to obesity, account for and accentuate the age-related decline in serum androgen levels. These issues are reviewed in a clinical perspective.

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Year:  2005        PMID： 16042355

Source DB:  PubMed          Journal:  J Endocrinol Invest        ISSN： 0391-4097            Impact factor:   4.256


  18 in total

1.  Distinct roles of age and abdominal visceral fat in reducing androgen receptor-dependent negative feedback on LH secretion in healthy men.

Authors:  P Y Takahashi; P Y Liu; J D Veldhuis
Journal:  Andrology       Date:  2014-04-30       Impact factor: 3.842

2.  Modification Effects of Changes in Job Demands on Associations Between Changes in Testosterone Levels and Andropause Symptoms: 2-Year Follow-up Study in Male Middle-Aged Japanese Workers.

Authors:  Kumi Hirokawa; Toshiyo Taniguchi; Yasuhito Fujii; Jiro Takaki; Akizumi Tsutsumi
Journal:  Int J Behav Med       Date:  2016-08

3.  Role of androgen receptor and associated lysine-demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer.

Authors:  Eric C Kauffman; Brian D Robinson; Martin J Downes; Leagh G Powell; Ming Ming Lee; Douglas S Scherr; Lorraine J Gudas; Nigel P Mongan
Journal:  Mol Carcinog       Date:  2011-03-11       Impact factor: 4.784

4.  Association of testosterone levels with socio-demographic characteristics in a sample of Ugandan men.

Authors:  Miriam Nansunga; Yukari C Manabe; Paul E Alele; Josephine Kasolo
Journal:  Afr Health Sci       Date:  2014-06       Impact factor: 0.927

5.  Monitoring testosterone replacement therapy with transdermal gel: when and how?

Authors:  A Sansone; M Sansone; R Selleri; A Schiavo; D Gianfrilli; C Pozza; M Zitzmann; A Lenzi; F Romanelli
Journal:  J Endocrinol Invest       Date:  2019-07-02       Impact factor: 4.256

6.  The natural history of symptomatic androgen deficiency in men: onset, progression, and spontaneous remission.

Authors:  Thomas G Travison; Rebecca Shackelton; Andre B Araujo; Susan A Hall; Rachel E Williams; Richard V Clark; Amy B O'Donnell; John B McKinlay
Journal:  J Am Geriatr Soc       Date:  2008-05       Impact factor: 5.562

7.  Erectile dysfunction and its management in patients with diabetes mellitus.

Authors:  Giuseppe Defeudis; Daniele Gianfrilli; Chiara Di Emidio; Riccardo Pofi; Dario Tuccinardi; Andrea Palermo; Andrea Lenzi; Paolo Pozzilli
Journal:  Rev Endocr Metab Disord       Date:  2015-10-26       Impact factor: 6.514

8.  Genetic influence on the association between bone mineral density and testosterone in Korean men.

Authors:  J Shin; J Sung; K Lee; Y-M Song
Journal:  Osteoporos Int       Date:  2015-09-02       Impact factor: 4.507

Review 9.  Biomedical consequences of alcohol use disorders in the HIV-infected host.

Authors:  Patricia E Molina; Gregory J Bagby; Steve Nelson
Journal:  Curr HIV Res       Date:  2014       Impact factor: 1.581

10.  The SIAMS-ED Trial: A National, Independent, Multicentre Study on Cardiometabolic and Hormonal Impairment of Men with Erectile Dysfunction Treated with Vardenafil.

Authors:  Andrea M Isidori; Giovanni Corona; Antonio Aversa; Daniele Gianfrilli; Emmanuele A Jannini; Carlo Foresta; Mario Maggi; Andrea Lenzi
Journal:  Int J Endocrinol       Date:  2014-05-15       Impact factor: 3.257
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