Literature DB >> 16041137

Koshikamide A2, a cytotoxic linear undecapeptide isolated from a marine sponge of Theonella sp.

Takahiro Araki1, Shigeki Matsunaga, Nobuhiro Fusetani.   

Abstract

Koshikamide A2 (2) was isolated as a cytotoxic metabolite from a marine sponge of Theonella sp. Its structure was elucidated to be a linear undecapeptide by spectroscopic and chemical methods, together with enzymatic conversion to known koshikamide A1 (1). The new peptide moderately inhibited the growth of P388 murine leukemia cells.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 16041137     DOI: 10.1271/bbb.69.1318

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  4 in total

Review 1.  Marine natural product peptides with therapeutic potential: Chemistry, biosynthesis, and pharmacology.

Authors:  Vedanjali Gogineni; Mark T Hamann
Journal:  Biochim Biophys Acta Gen Subj       Date:  2017-08-24       Impact factor: 3.770

2.  Mutremdamide A and koshikamides C-H, peptide inhibitors of HIV-1 entry from different Theonella species.

Authors:  Alberto Plaza; Giuseppe Bifulco; Milena Masullo; John R Lloyd; Jessica L Keffer; Patrick L Colin; John N A Hooper; Lori J Bell; Carole A Bewley
Journal:  J Org Chem       Date:  2010-07-02       Impact factor: 4.354

Review 3.  Antitumor peptides from marine organisms.

Authors:  Lan-Hong Zheng; Yue-Jun Wang; Jun Sheng; Fang Wang; Yuan Zheng; Xiu-Kun Lin; Mi Sun
Journal:  Mar Drugs       Date:  2011-10-10       Impact factor: 6.085

Review 4.  Natural products from the Lithistida: a review of the literature since 2000.

Authors:  Priscilla L Winder; Shirley A Pomponi; Amy E Wright
Journal:  Mar Drugs       Date:  2011-12-15       Impact factor: 6.085

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.