Literature DB >> 16040159

Synthesis and biological activity of novel acridinylidene and benzylidene thiazolidinediones.

R H Mourão1, T G Silva, A L M Soares, E S Vieira, J N Santos, M C A Lima, V L M Lima, S L Galdino, J Barbe, I R Pitta.   

Abstract

A novel set of acridinylidene thiazolidinediones and benzylidene thiazolidinediones was synthesized by nucleophilic addition of cyanoacrylates. Some of these compounds were evaluated for their glucose lowering capability and their effects on the triglyceride level in alloxan diabetic mice.

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Year:  2005        PMID： 16040159     DOI： 10.1016/j.ejmech.2005.06.002

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  6 in total

1.  Enhanced antiproliferative activity of the new anticancer candidate LPSF/AC04 in cyclodextrin inclusion complexes encapsulated into liposomes.

Authors:  Elisângela A M Mendonça; Mariane C B Lira; Marcelo M Rabello; Isabella M F Cavalcanti; Suely L Galdino; Ivan R Pitta; Maria do Carmo A Lima; Maira G R Pitta; Marcelo Z Hernandes; Nereide S Santos-Magalhães
Journal:  AAPS PharmSciTech       Date:  2012-10-02       Impact factor: 3.246

2.  Thermodynamic Characterization of Mixed Monolayers of a Novel Oxazolidine Derivative and Phospholipids.

Authors:  Felipe de Sá Rocha; Rafael Ramos da Silva; Gustavo Henrique Ribeiro Codeceira; Maria do Carmo Alves de Lima; Ivan da Rocha Pitta; Maria Danielly Lima de Oliveira; César Augusto Souza de Andrade
Journal:  J Membr Biol       Date:  2018-10-03       Impact factor: 1.843

3.  LPSF/GQ-02 inhibits the development of hepatic steatosis and inflammation in a mouse model of non-alcoholic fatty liver disease (NAFLD).

Authors:  Amanda Karolina Soares e Silva; Dilênia de Oliveira Cipriano Torres; Fabiana Oliveira dos Santos Gomes; Bruna dos Santos Silva; Edlene Lima Ribeiro; Amanda Costa Oliveira; Laise Aline Martins dos Santos; Maria do Carmo Alves de Lima; Ivan da Rocha Pitta; Christina Alves Peixoto
Journal:  PLoS One       Date:  2015-04-14       Impact factor: 3.240

4.  CHARMM Force Field Parameterization of Peroxisome Proliferator-Activated Receptor γ Ligands.

Authors:  Melina Mottin; Paulo C T Souza; Clarisse G Ricci; Munir S Skaf
Journal:  Int J Mol Sci       Date:  2016-12-22       Impact factor: 5.923

5.  Synthesis and biological evaluation of novel imidazolidine derivatives as candidates to schistosomicidal agents.

Authors:  Thiago José Matos-Rocha; Maria do Carmo Alves de Lima; Anekécia Lauro da Silva; Jamerson Ferreira de Oliveira; Allana Lemos Andrade Gouveia; Vinícius Barros Ribeiro da Silva; Antônio Sérgio Alves de Almeida; Fábio André Brayner; Pablo Ramon Gualberto Cardoso; Marina da Rocha Pitta-Galdino; Ivan da Rocha Pitta; Moacyr Jesus Barreto de Melo Rêgo; Luiz Carlos Alves; Maira Galdino da Rocha Pitta
Journal:  Rev Inst Med Trop Sao Paulo       Date:  2017-04-03       Impact factor: 1.846

6.  GQ-16, a novel peroxisome proliferator-activated receptor γ (PPARγ) ligand, promotes insulin sensitization without weight gain.

Authors:  Angélica A Amato; Senapathy Rajagopalan; Jean Z Lin; Bruno M Carvalho; Ana C M Figueira; Jenny Lu; Stephen D Ayers; Melina Mottin; Rodrigo L Silveira; Paulo C T Souza; Rosa H V Mourão; Mário J A Saad; Marie Togashi; Luiz A Simeoni; Dulcinéia S P Abdalla; Munir S Skaf; Igor Polikparpov; Maria C A Lima; Suely L Galdino; Richard G Brennan; John D Baxter; Ivan R Pitta; Paul Webb; Kevin J Phillips; Francisco A R Neves
Journal:  J Biol Chem       Date:  2012-05-14       Impact factor: 5.157
  6 in total

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