Literature DB >> 16039560

Phosphoinositide lipid second messengers: new paradigms for calcium channel modulation.

Patrick Delmas1, Bertrand Coste, Nikita Gamper, Mark S Shapiro.   

Abstract

Neuronal Ca2+ channels are key transducers coupling excitability to cellular function. As such, they are tightly regulated by multiple G protein-signaling pathways that finely tune their activity. In addition to fast, direct G(beta)gamma modulation of Ca2+ channels, a slower Galpha(q/11)-mediated mechanism has remained enigmatic despite intensive study. Recent work suggests that membrane phosphoinositides are crucial determinants of Ca2+ channel activity. Here, we discuss their role in Ca2+ channel modulation and the leading theories that seek to elucidate the underlying molecular details of the so-called "mysterious" G(q/11)-mediated signal.

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Year:  2005        PMID： 16039560     DOI： 10.1016/j.neuron.2005.07.001

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  42 in total

Review 1.  The ß subunit of voltage-gated Ca2+ channels.

Authors:  Zafir Buraei; Jian Yang
Journal:  Physiol Rev       Date:  2010-10       Impact factor: 37.312

2.  Membrane-localized β-subunits alter the PIP2 regulation of high-voltage activated Ca2+ channels.

Authors:  Byung-Chang Suh; Dong-Il Kim; Björn H Falkenburger; Bertil Hille
Journal:  Proc Natl Acad Sci U S A       Date:  2012-02-02       Impact factor: 11.205

Review 3.  Regulation of TRP channels by PIP(2).

Authors:  Tibor Rohacs
Journal:  Pflugers Arch       Date:  2006-10-10       Impact factor: 3.657

4.  Alternative splicing controls G protein-dependent inhibition of N-type calcium channels in nociceptors.

Authors:  Jesica Raingo; Andrew J Castiglioni; Diane Lipscombe
Journal:  Nat Neurosci       Date:  2007-02-11       Impact factor: 24.884

5.  Receptor-specific inhibition of GABAB-activated K+ currents by muscarinic and metabotropic glutamate receptors in immature rat hippocampus.

Authors:  Jong-Woo Sohn; Doyun Lee; Hana Cho; Wonil Lim; Hee-Sup Shin; Suk-Ho Lee; Won-Kyung Ho
Journal:  J Physiol       Date:  2007-01-25       Impact factor: 5.182

6.  Target-specific PIP(2) signalling: how might it work?

Authors:  Nikita Gamper; Mark S Shapiro
Journal:  J Physiol       Date:  2007-04-05       Impact factor: 5.182

7.  Agonist-induced localization of Gq-coupled receptors and G protein-gated inwardly rectifying K+ (GIRK) channels to caveolae determines receptor specificity of phosphatidylinositol 4,5-bisphosphate signaling.

Authors:  Shanyu Cui; Won-Kyung Ho; Seong-Tae Kim; Hana Cho
Journal:  J Biol Chem       Date:  2010-11-01       Impact factor: 5.157

8.  Arachidonic acid release mediated by OX1 orexin receptors.

Authors:  Pauli M Turunen; Marie E Ekholm; Pentti Somerharju; Jyrki P Kukkonen
Journal:  Br J Pharmacol       Date:  2009-12-04       Impact factor: 8.739

Review 9.  Regulation of transient receptor potential (TRP) channels by phosphoinositides.

Authors:  Tibor Rohacs; Bernd Nilius
Journal:  Pflugers Arch       Date:  2007-05-04       Impact factor: 3.657

Review 10.  Regulation of Ca(V)2 calcium channels by G protein coupled receptors.

Authors:  Gerald W Zamponi; Kevin P M Currie
Journal:  Biochim Biophys Acta       Date:  2012-10-12
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