Literature DB >> 16039237

Cell therapy plus transmyocardial laser revascularization for refractory angina.

Luís Henrique W Gowdak1, Isolmar T Schettert, Carlos Eduardo Rochitte, Luiz Augusto F Lisboa, Luís Alberto O Dallan, Luiz Antônio M César, José Eduardo Krieger, José Antônio F Ramires, Sérgio A de Oliveira.   

Abstract

We describe the use of autologous bone marrow cells combined with transmyocardial laser revascularization in a 74-year-old man with refractory angina. Baseline cardiac magnetic resonance imaging revealed a markedly depressed left ventricle systolic function and an extensive area of myocardial ischemia. During surgery, 11 laser shots using a CO2 Heart Laser System (PLC Medical Systems, Milford, MA) were fired and a 5-mL cell suspension containing 21.5 x 10(6) bone marrow cells/mL was delivered by multiple injections into the myocardium. At 6 months after the procedure, another cardiac magnetic resonance imaging showed an almost complete resolution of the perfusion defect and an improvement in left ventricular contractility.

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Year:  2005        PMID: 16039237     DOI: 10.1016/j.athoracsur.2005.04.080

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  5 in total

1.  Mid term results after bone marrow laser revascularization for treating refractory angina.

Authors:  Guillermo Reyes; Keith B Allen; Pablo Alvarez; Adrian Alegre; Beatriz Aguado; MariaJose Olivera; Paloma Caballero; JoseLuis Rodríguez; Juan Duarte
Journal:  BMC Cardiovasc Disord       Date:  2010-09-17       Impact factor: 2.298

2.  Multicenter randomized trial of cell therapy in cardiopathies - MiHeart Study.

Authors:  Bernardo R Tura; Helena F Martino; Luis H Gowdak; Ricardo Ribeiro dos Santos; Hans F Dohmann; José E Krieger; Gilson Feitosa; Fábio Vilas-Boas; Sérgio A Oliveira; Suzana A Silva; Augusto Z Bozza; Radovan Borojevic; Antonio C Campos de Carvalho
Journal:  Trials       Date:  2007-01-18       Impact factor: 2.279

Review 3.  Transmyocardial revascularization devices: technology update.

Authors:  Bogdan A Kindzelski; Yifu Zhou; Keith A Horvath
Journal:  Med Devices (Auckl)       Date:  2014-12-18

4.  Cell-Based Therapies for Heart Failure.

Authors:  Antonio Carlos Campos de Carvalho; Tais H Kasai-Brunswick; Adriana Bastos Carvalho
Journal:  Front Pharmacol       Date:  2021-04-12       Impact factor: 5.810

Review 5.  Remodeling an infarcted heart: novel hybrid treatment with transmyocardial revascularization and stem cell therapy.

Authors:  Jessika Iwanski; Raymond K Wong; Douglas F Larson; Alice S Ferng; Raymond B Runyan; Steven Goldstein; Zain Khalpey
Journal:  Springerplus       Date:  2016-06-16
  5 in total

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