| Literature DB >> 16039121 |
Serhan Boduroglu1, Jouliana M El Khoury, D Venkat Reddy, Peter L Rinaldi, Jun Hu.
Abstract
3-Pyridinylboronic acid is identified as a key sensing element for reversible sugar complexation in an aqueous solution at the physiological pH. The utility of a sensing element has been demonstrated through a simple colorimetric titration of glucose using absorption spectroscopy in the visible region. The mechanism of the high diol/triol binding affinity of pyridine boronic acid in the neutral pH is discussed based on the 1H and 11B NMR spectroscopic studies.Entities:
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Year: 2005 PMID: 16039121 DOI: 10.1016/j.bmcl.2005.05.075
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823