Literature DB >> 16038571

Medication-related problems in the elderly : defining the issues and identifying solutions.

William Simonson1, Janice L Feinberg.   

Abstract

The elderly population is at great risk for medication-related problems as a result of age-related physiological changes, the presence of multiple chronic diseases and conditions, and the types and numbers of prescription and nonprescription medications they consume.Medication-related problems have received international attention. In the US, as many as 200,000 people may die of medication-related problems each year. Studies from other developed nations where patients have access to medications have determined that various types of medication-related problems occur in the elderly population in health care environments ranging from nursing homes to community dwelling settings.A variety of initiatives have been developed in an attempt to reduce the likelihood of medication-related problems in the elderly. The role that a pharmacist can play in identifying and preventing the negative health outcomes and costs of medication-related problems is being increasingly recognised. Indeed, numerous studies have now documented the positive impact that pharmacists can have in this area, and ongoing research is being conducted. With the growing numbers of elderly, and the increase in the numbers and types of medications available, it is imperative that awareness of medication-related problems be increased and that further initiatives be developed to optimise the positive outcomes of drug therapy in the elderly.

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Year:  2005        PMID: 16038571     DOI: 10.2165/00002512-200522070-00002

Source DB:  PubMed          Journal:  Drugs Aging        ISSN: 1170-229X            Impact factor:   3.923


  40 in total

1.  Risk factors for adverse drug events among nursing home residents.

Authors:  T S Field; J H Gurwitz; J Avorn; D McCormick; S Jain; M Eckler; M Benser; D W Bates
Journal:  Arch Intern Med       Date:  2001-07-09

2.  Quality indicators for appropriate medication use in vulnerable elders.

Authors:  E L Knight; J Avorn
Journal:  Ann Intern Med       Date:  2001-10-16       Impact factor: 25.391

Review 3.  Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications.

Authors:  A A Mangoni; S H D Jackson
Journal:  Br J Clin Pharmacol       Date:  2004-01       Impact factor: 4.335

Review 4.  Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine.

Authors:  M H Beers; J G Ouslander; I Rollingher; D B Reuben; J Brooks; J C Beck
Journal:  Arch Intern Med       Date:  1991-09

5.  Inappropriate drug prescriptions for elderly residents of board and care facilities.

Authors:  D L Spore; V Mor; P Larrat; C Hawes; J Hiris
Journal:  Am J Public Health       Date:  1997-03       Impact factor: 9.308

6.  Incidence and preventability of adverse drug events among older persons in the ambulatory setting.

Authors:  Jerry H Gurwitz; Terry S Field; Leslie R Harrold; Jeffrey Rothschild; Kristin Debellis; Andrew C Seger; Cynthia Cadoret; Leslie S Fish; Lawrence Garber; Michael Kelleher; David W Bates
Journal:  JAMA       Date:  2003-03-05       Impact factor: 56.272

7.  Medication use and the elderly: current status and opportunities.

Authors:  J Avorn
Journal:  Health Aff (Millwood)       Date:  1995       Impact factor: 6.301

8.  Adverse drug reaction risk factors in older outpatients.

Authors:  Emily R Hajjar; Joseph T Hanlon; Margaret B Artz; Catherine I Lindblad; Carl F Pieper; Richard J Sloane; Christine M Ruby; Kenneth E Schmader
Journal:  Am J Geriatr Pharmacother       Date:  2003-12

9.  Medication-related problems commonly occurring in an Australian community setting.

Authors:  E E Roughead; J D Barratt; A L Gilbert
Journal:  Pharmacoepidemiol Drug Saf       Date:  2004-02       Impact factor: 2.890

10.  Potentially inappropriate prescribing in Ontario community-dwelling older adults and nursing home residents.

Authors:  Christopher J Lane; Susan E Bronskill; Kathy Sykora; Irfan A Dhalla; Geoffrey M Anderson; Muhammad M Mamdani; Sudeep S Gill; Jerry H Gurwitz; Paula A Rochon
Journal:  J Am Geriatr Soc       Date:  2004-06       Impact factor: 5.562

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  39 in total

1.  Usually Available Clinical and Laboratory Data Are Insufficient for a Valid Medication Review: A Crossover Study.

Authors:  K P G M Hurkens; C Mestres-Gonzalvo; H A J M de Wit; P H M van der Kuy; R Janknegt; F Verhey; J M G A Schols; C D A Stehouwer; B Winkens; W Mulder
Journal:  J Nutr Health Aging       Date:  2016-01       Impact factor: 4.075

Review 2.  Pharmacists' interventions for optimization of medication use in nursing homes : a systematic review.

Authors:  Charlotte L R Verrue; Mirko Petrovic; Els Mehuys; Jean Paul Remon; Robert Vander Stichele
Journal:  Drugs Aging       Date:  2009       Impact factor: 3.923

3.  Drug-related problems identified in medication reviews by Australian pharmacists.

Authors:  Andrew C Stafford; Peter C Tenni; Gregory M Peterson; Shane L Jackson; Anne Hejlesen; Christine Villesen; Mette Rasmussen
Journal:  Pharm World Sci       Date:  2009-02-26

Review 4.  Pharmacologic options in the management of upper gastrointestinal bleeding: focus on the elderly.

Authors:  Moe Htet Kyaw; Francis Ka Leung Chan
Journal:  Drugs Aging       Date:  2014-05       Impact factor: 3.923

5.  Potentially inappropriate prescribing to the elderly: comparison of new protocol to Beers criteria with relation to hospitalizations for ADRs.

Authors:  Suzana Mimica Matanović; Vera Vlahović-Palčevski
Journal:  Eur J Clin Pharmacol       Date:  2014-01-24       Impact factor: 2.953

6.  Polypharmacy, length of hospital stay, and in-hospital mortality among elderly patients in internal medicine wards. The REPOSI study.

Authors:  Alessandro Nobili; Giuseppe Licata; Francesco Salerno; Luca Pasina; Mauro Tettamanti; Carlotta Franchi; Luigi De Vittorio; Alessandra Marengoni; Salvatore Corrao; Alfonso Iorio; Maura Marcucci; Pier Mannuccio Mannucci
Journal:  Eur J Clin Pharmacol       Date:  2011-01-11       Impact factor: 2.953

7.  Pharmaceutical care model to assess the medication-related risks of travel.

Authors:  Ian M Heslop; Michelle Bellingan; Richard Speare; Beverley D Glass
Journal:  Int J Clin Pharm       Date:  2014-10-01

Review 8.  Inappropriate prescribing: a systematic overview of published assessment tools.

Authors:  Carole P Kaufmann; Regina Tremp; Kurt E Hersberger; Markus L Lampert
Journal:  Eur J Clin Pharmacol       Date:  2013-09-10       Impact factor: 2.953

9.  Medication non-adherence among elderly patients newly discharged and receiving polypharmacy.

Authors:  L Pasina; A L Brucato; C Falcone; E Cucchi; A Bresciani; M Sottocorno; G C Taddei; M Casati; C Franchi; C D Djade; A Nobili
Journal:  Drugs Aging       Date:  2014-04       Impact factor: 3.923

10.  The effect on medication errors of pharmacists charting medication in an emergency department.

Authors:  Hayley M Vasileff; Lauren E Whitten; Jennifer A Pink; Sharon J Goldsworthy; Manya T Angley
Journal:  Pharm World Sci       Date:  2008-11-29
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