Literature DB >> 16036040

Current concepts for the neurohormonal management of left ventricular dysfunction after myocardial infarction.

Keyur B Shah1, Stephen S Gottlieb.   

Abstract

The importance of addressing neurohormonal activation in patients after a myocardial infarction is now well-appreciated. Inhibition of the renin-angiotensin-aldosterone axis and the sympathetic nervous system can result in improved cardiac function and survival. As we learn more about other systems, we should be able to realize further benefits. In particular, the roles of endothelin, matrix metalloproteinases, and cytokines in remodeling are being investigated, with the potential to result in better outcomes for patients.

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Year:  2004        PMID： 16036040     DOI： 10.1007/s11897-004-0004-9

Source DB:  PubMed          Journal:  Curr Heart Fail Rep        ISSN： 1546-9530


  55 in total

1.  Myocardial and interstitial matrix metalloproteinase activity after acute myocardial infarction in pigs.

Authors:  T Etoh; C Joffs; A M Deschamps; J Davis; K Dowdy; J Hendrick; S Baicu; R Mukherjee; M Manhaini; F G Spinale
Journal:  Am J Physiol Heart Circ Physiol       Date:  2001-09       Impact factor: 4.733

2.  Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: insights from the randomized aldactone evaluation study (RALES). Rales Investigators.

Authors:  F Zannad; F Alla; B Dousset; A Perez; B Pitt
Journal:  Circulation       Date:  2000-11-28       Impact factor: 29.690

3.  Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat.

Authors:  J T Peterson; H Li; L Dillon; J W Bryant
Journal:  Cardiovasc Res       Date:  2000-05       Impact factor: 10.787

4.  Cytokines and cytokine receptors in advanced heart failure: an analysis of the cytokine database from the Vesnarinone trial (VEST).

Authors:  A Deswal; N J Petersen; A M Feldman; J B Young; B G White; D L Mann
Journal:  Circulation       Date:  2001-04-24       Impact factor: 29.690

5.  Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure.

Authors:  S Kim; M Yoshiyama; Y Izumi; H Kawano; M Kimoto; Y Zhan; H Iwao
Journal:  Circulation       Date:  2001-01-02       Impact factor: 29.690

6.  Aldosterone inhibition limits collagen synthesis and progressive left ventricular enlargement after anterior myocardial infarction.

Authors:  M G Modena; P Aveta; A Menozzi; R Rossi
Journal:  Am Heart J       Date:  2001-01       Impact factor: 4.749

7.  beta-adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling.

Authors:  S D Prabhu; B Chandrasekar; D R Murray; G L Freeman
Journal:  Circulation       Date:  2000-05-02       Impact factor: 29.690

8.  1999 update: ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction).

Authors:  T J Ryan; E M Antman; N H Brooks; R M Califf; L D Hillis; L F Hiratzka; E Rapaport; B Riegel; R O Russell; E E Smith; W D Weaver; R J Gibbons; J S Alpert; K A Eagle; T J Gardner; A Garson; G Gregoratos; T J Ryan; S C Smith
Journal:  J Am Coll Cardiol       Date:  1999-09       Impact factor: 24.094

9.  The effect of the angiotensin-converting-enzyme inhibitor zofenopril on mortality and morbidity after anterior myocardial infarction. The Survival of Myocardial Infarction Long-Term Evaluation (SMILE) Study Investigators.

Authors:  E Ambrosioni; C Borghi; B Magnani
Journal:  N Engl J Med       Date:  1995-01-12       Impact factor: 91.245

10.  Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both.

Authors:  Marc A Pfeffer; John J V McMurray; Eric J Velazquez; Jean-Lucien Rouleau; Lars Køber; Aldo P Maggioni; Scott D Solomon; Karl Swedberg; Frans Van de Werf; Harvey White; Jeffrey D Leimberger; Marc Henis; Susan Edwards; Steven Zelenkofske; Mary Ann Sellers; Robert M Califf
Journal:  N Engl J Med       Date:  2003-11-10       Impact factor: 91.245
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