Literature DB >> 16035207

Mother and fetus both survive from severe paraquat intoxication.

Chang-Chyi Jenq1, Chien-Der Wu, Ja-Liang Lin.   

Abstract

Paraquat, 1,1'-dimethyl-4,4'-bipyridylium dichloride, is a commonly applied bipyridyl contact herbicide. Paraquat poisoning from suicidal ingestion causes high mortality rates, and severe poisoning has been uniformly fatal in pregnant females (nine of nine cases). We presented a case of severe paraquat poisoning from suicidal ingestion in a woman in the third trimester of pregnancy (G5P4A1). Urine dithionate test was strongly positive (showed dark blue color). She was managed with charcoal hemoperfusion x 2, megadose of cyclophosphamide, and methylprednisolone pulse therapy. Despite initial deterioration of renal and liver function, she had a normal spontaneous delivery of a healthy girl baby 14 weeks after the exposure. The child reached developmental milestones normally and appeared healthy and well nourished at age 5. This may be the first documentation of a pregnant woman with moderate to severe paraquat poisoning successfully delivering a healthy baby.

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Year:  2005        PMID: 16035207

Source DB:  PubMed          Journal:  Clin Toxicol (Phila)        ISSN: 1556-3650            Impact factor:   4.467


  3 in total

1.  Fetal poisoning after maternal paraquat ingestion during third trimester of pregnancy: case report and literature review.

Authors:  Chulathida Chomchai; Anongrat Tiawilai
Journal:  J Med Toxicol       Date:  2007-12

2.  Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand.

Authors:  Pajaree Konthonbut; Pornpimol Kongtip; Noppanun Nankongnab; Mathuros Tipayamongkholgul; Witaya Yoosook; Susan Woskie
Journal:  Int J Environ Res Public Health       Date:  2018-06-03       Impact factor: 3.390

3.  Fetal outcomes after intentional ingestion of paraquat: A case report.

Authors:  Jianshi Chen; Xiangdong Jian; Guangcai Yu; Min Si; Baotian Kan
Journal:  Medicine (Baltimore)       Date:  2020-01       Impact factor: 1.817

  3 in total

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