| Literature DB >> 16029938 |
Rumi Fujita1, Jie Liu, Kuniyoshi Shimizu, Fumiko Konishi, Kiyoshi Noda, Shoichiro Kumamoto, Chie Ueda, Hisatoshi Tajiri, Shuhei Kaneko, Yoshitaro Suimi, Ryuichiro Kondo.
Abstract
The inhibitory effects of methanol extracts of 19 edible and medicinal mushrooms on 5alpha-reductase activity were examined. The extract of Ganoderma lucidum Fr. Krast (Ganodermataceae) showed the strongest 5alpha-reductase inhibitory activity. The treatment of the fruit body of Ganoderma lucidum or the extract prepared from it significantly inhibited the testosterone-induced growth of the ventral prostate in castrated rats. These results showed that Ganoderma lucidum might be a useful ingredient for the treatment of benign prostatic hyperplasia (BPH).Entities:
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Year: 2005 PMID： 16029938 DOI： 10.1016/j.jep.2005.05.041
Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360