Literature DB >> 1602970

Alternatives to Aroclor 1254-induced S9 in in vitro genotoxicity assays.

B M Elliott1, R D Combes, C R Elcombe, D G Gatehouse, G G Gibson, J M Mackay, R C Wolf.   

Abstract

A working party was set up by the UK Environmental Mutagen Society to consider alternatives to Aroclor 1254 (Aroclor)-induced S9 in in vitro genotoxicity assays, with the aims of considering whether a replacement for Aroclor in its role in general screening assays could be readily identified. The working party concluded that there was sufficient support in the literature to justify the use of an appropriate phenobarbital/beta-naphthoflavone regime as an acceptable alternative to Aroclor.

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Year:  1992        PMID: 1602970     DOI: 10.1093/mutage/7.3.175

Source DB:  PubMed          Journal:  Mutagenesis        ISSN: 0267-8357            Impact factor:   3.000


  2 in total

1.  Investigating the mutagenic effects of three commonly used pulpotomy agents using the ames test.

Authors:  Mohammad Samiei; Saeed Asgary; Malak Farajzadeh; Nasrin Bargahi; Majid Abdolrahimi; Usef Kananizadeh; Siavoush Dastmalchi
Journal:  Adv Pharm Bull       Date:  2015-03-05

Review 2.  Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation.

Authors:  Marjory Moreau; Pankajini Mallick; Marci Smeltz; Saad Haider; Chantel I Nicolas; Salil N Pendse; Jeremy A Leonard; Matthew W Linakis; Patrick D McMullen; Rebecca A Clewell; Harvey J Clewell; Miyoung Yoon
Journal:  Front Toxicol       Date:  2022-04-29
  2 in total

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