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Literature DB >> 16029056

Targeted drug delivery in cancer therapy.

Abstract

Chemotherapy has been the main modality of treatment for cancer patients; however, its success rate remains low, primarily due to limited accessibility of drugs to the tumor tissue, their intolerable toxicity, development of multi-drug resistance, and the dynamic heterogeneous biology of the growing tumors. Better understanding of tumor biology in recent years and new targeted drug delivery approaches that are being explored using different nanosystems and bioconjugates provide optimism in developing successful cancer therapy. This article reviews the possibilities and challenges for targeted drug delivery in cancer therapy.

Entities: Disease Species

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Year: 2005 PMID： 16029056 DOI： 10.1177/153303460500400405

Source DB: PubMed Journal: Technol Cancer Res Treat ISSN： 1533-0338

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Cited

45 in total

1. Immunocolloidal targeting of the endocytotic siglec-7 receptor using peripheral attachment of siglec-7 antibodies to poly(lactide-co-glycolide) nanoparticles.

Authors: Christopher J Scott; Waleed M Marouf; Derek J Quinn; Richard J Buick; Selinda J Orr; Ryan F Donnelly; Paul A McCarron
Journal: Pharm Res Date: 2007-08-03 Impact factor: 4.200

Review 2. Nanomedicine: clinical applications of polyethylene glycol conjugated proteins and drugs.

Authors: Suphiya Parveen; Sanjeeb K Sahoo
Journal: Clin Pharmacokinet Date: 2006 Impact factor: 6.447

3. Studies of the cellular uptake of hydrogel nanospheres and microspheres by phagocytes, vascular endothelial cells, and smooth muscle cells.

Authors: Kytai Truong Nguyen; Kajal P Shukla; Miriam Moctezuma; Arthur R C Braden; Jun Zhou; Zhibing Hu; Liping Tang
Journal: J Biomed Mater Res A Date: 2009-03-15 Impact factor: 4.396

Review 4. The application of nanotechnology in enhancing immunotherapy for cancer treatment: current effects and perspective.

Authors: Yongjiang Li; Ciceron Ayala-Orozco; Pradipta Ranjan Rauta; Sunil Krishnan
Journal: Nanoscale Date: 2019-09-18 Impact factor: 7.790

5. ABCG2 aptamer selectively delivers doxorubicin to drug-resistant breast cancer cells.

Authors: Shirin Hashemitabar; Rezvan Yazdian-Robati; Maryam Hashemi; Mohammad Ramezani; Khalil Abnous; Fatemeh Kalalinia
Journal: J Biosci Date: 2019-06 Impact factor: 1.826

6. A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation.

Authors: Savita Bisht; Mehtab A Khan; Mena Bekhit; Haibo Bai; Toby Cornish; Masamichi Mizuma; Michelle A Rudek; Ming Zhao; Amarnath Maitra; Balmiki Ray; Debomoy Lahiri; Anirban Maitra; Robert A Anders
Journal: Lab Invest Date: 2011-06-20 Impact factor: 5.662

Targeted drug delivery in cancer therapy.

1. Immunocolloidal targeting of the endocytotic siglec-7 receptor using peripheral attachment of siglec-7 antibodies to poly(lactide-co-glycolide) nanoparticles.

Review 2. Nanomedicine: clinical applications of polyethylene glycol conjugated proteins and drugs.

3. Studies of the cellular uptake of hydrogel nanospheres and microspheres by phagocytes, vascular endothelial cells, and smooth muscle cells.

Review 4. The application of nanotechnology in enhancing immunotherapy for cancer treatment: current effects and perspective.

5. ABCG2 aptamer selectively delivers doxorubicin to drug-resistant breast cancer cells.

6. A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation.

7. On the toxicity of therapeutically used nanoparticles: an overview.

Review 8. Bioengineering strategies for designing targeted cancer therapies.

9. Liposomes targeted by fusion phage proteins.

Review 10. Phage protein-targeted cancer nanomedicines.