Literature DB >> 16028562

DNA methylation, genomic silencing, and links to nutrition and cancer.

Dale C McCabe1, Marie A Caudill.   

Abstract

DNA methylation is a heritable epigenetic feature that is associated with transcriptional silencing, X-chromosome inactivation, genetic imprinting, and genomic stability. The addition of the methyl group is catalyzed by a family of DNA methyltransferases whose co-substrates are DNA and S-adenosylmethionine, the latter being derived from the methionine cycle. Aberrant DNA methylation is linked to numerous pathologies, including cancer. The purpose of this review is to describe DNA methylation and its functions, to examine the relationship between dietary methyl insufficiency and DNA methylation, and to evaluate the associations between DNA methylation and cancer.

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Year:  2005        PMID: 16028562     DOI: 10.1301/nr.2005.jun.183-195

Source DB:  PubMed          Journal:  Nutr Rev        ISSN: 0029-6643            Impact factor:   7.110


  23 in total

1.  Alcohol-associated folate disturbances result in altered methylation of folate-regulating genes.

Authors:  Nissar Ahmad Wani; Abid Hamid; Jyotdeep Kaur
Journal:  Mol Cell Biochem       Date:  2011-12-07       Impact factor: 3.396

Review 2.  A potential role of probiotics in colorectal cancer prevention: review of possible mechanisms of action.

Authors:  Esther Swee Lan Chong
Journal:  World J Microbiol Biotechnol       Date:  2013-09-26       Impact factor: 3.312

3.  Folate bioavailability: implications for establishing dietary recommendations and optimizing status.

Authors:  Marie A Caudill
Journal:  Am J Clin Nutr       Date:  2010-03-10       Impact factor: 7.045

4.  Positional effects revealed in Illumina methylation array and the impact on analysis.

Authors:  Chuan Jiao; Chunling Zhang; Rujia Dai; Yan Xia; Kangli Wang; Gina Giase; Chao Chen; Chunyu Liu
Journal:  Epigenomics       Date:  2018-02-22       Impact factor: 4.778

5.  Choline intake exceeding current dietary recommendations preserves markers of cellular methylation in a genetic subgroup of folate-compromised men.

Authors:  William Shin; Jian Yan; Christian M Abratte; Francoise Vermeylen; Marie A Caudill
Journal:  J Nutr       Date:  2010-03-10       Impact factor: 4.798

6.  Epimutations, inheritance and causes of aberrant DNA methylation in cancer.

Authors:  David Mossman; Rodney J Scott
Journal:  Hered Cancer Clin Pract       Date:  2006-05-15       Impact factor: 2.857

7.  Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic women.

Authors:  Unhee Lim; Andrew Flood; Sang-Woon Choi; Demetrius Albanes; Amanda J Cross; Arthur Schatzkin; Rashmi Sinha; Hormuzd A Katki; Brooks Cash; Phillip Schoenfeld; Rachael Stolzenberg-Solomon
Journal:  Gastroenterology       Date:  2007-10-10       Impact factor: 22.682

8.  The MTHFR 677TT genotype and folate intake interact to lower global leukocyte DNA methylation in young Mexican American women.

Authors:  Juan Axume; Steven S Smith; Igor P Pogribny; David J Moriarty; Marie A Caudill
Journal:  Nutr Res       Date:  2007-01       Impact factor: 3.315

9.  Global leukocyte DNA methylation is similar in African American and Caucasian women under conditions of controlled folate intake.

Authors:  Juan Axume; Steven S Smith; Igor P Pogribny; David J Moriarty; Marie A Caudill
Journal:  Epigenetics       Date:  2007-02-27       Impact factor: 4.528

Review 10.  Decision Analysis of Transplantation for Patients with Myelodysplasia: "Who Should We Transplant Today?"

Authors:  Shukaib Arslan; Ryotaro Nakamura
Journal:  Curr Hematol Malig Rep       Date:  2020-08       Impact factor: 3.952

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