Literature DB >> 16028302

Strategies for the NMR-based identification and optimization of allosteric protein kinase inhibitors.

Wolfgang Jahnke1, Marcel J J Blommers, César Fernández, Christian Zwingelstein, René Amstutz.   

Abstract

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Year:  2005        PMID： 16028302     DOI： 10.1002/cbic.200500100

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  7 in total

1.  Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors.

Authors:  Jesus Vazquez; Lutz Tautz; Jennifer J Ryan; Kristiina Vuori; Tomas Mustelin; Maurizio Pellecchia
Journal:  J Med Chem       Date:  2007-03-30       Impact factor: 7.446

2.  Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor.

Authors:  John L Stebbins; Surya K De; Petra Pavlickova; Vida Chen; Thomas Machleidt; Li-Hsing Chen; Christian Kuntzen; Shinichi Kitada; Michael Karin; Maurizio Pellecchia
Journal:  J Med Chem       Date:  2011-08-23       Impact factor: 7.446

3.  Development of paramagnetic probes for molecular recognition studies in protein kinases.

Authors:  Jesus Vazquez; Surya K De; Li-Hsing Chen; Megan Riel-Mehan; Aras Emdadi; Jason Cellitti; John L Stebbins; Michele F Rega; Maurizio Pellecchia
Journal:  J Med Chem       Date:  2008-06-26       Impact factor: 7.446

Review 4.  Investigating metabolite-protein interactions: an overview of available techniques.

Authors:  Grace Xiaolu Yang; Xiyan Li; Michael Snyder
Journal:  Methods       Date:  2012-06-28       Impact factor: 3.608

Review 5.  Expanding the number of 'druggable' targets: non-enzymes and protein-protein interactions.

Authors:  Leah N Makley; Jason E Gestwicki
Journal:  Chem Biol Drug Des       Date:  2013-01       Impact factor: 2.817

Review 6.  Biomolecular NMR: a chaperone to drug discovery.

Authors:  Marco Betz; Krishna Saxena; Harald Schwalbe
Journal:  Curr Opin Chem Biol       Date:  2006-05-05       Impact factor: 8.822

Review 7.  Small molecule substrate phosphorylation site inhibitors of protein kinases: approaches and challenges.

Authors:  Meghan E Breen; Matthew B Soellner
Journal:  ACS Chem Biol       Date:  2014-12-23       Impact factor: 5.100
  7 in total

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