Literature DB >> 16027870

C-terminal Pro-Gly-Pro tripeptide in contrast to full-length neuropeptide semax exhibits no neuroprotective effect in experimental cerebral ischemia.

O E Fadyukova1, A Kadi, Ou Bai, G M Andzhusheva, V B Koshelev.   

Abstract

The C-terminal fragment Pro-Gly-Pro of semax does not modulate the development of symptoms of neurological deficiency and mortality in rats with incomplete global cerebral ischemia. Hence, previously revealed neuroprotective effects of semax are mainly determined by corticotropin ACTH4-7 fragment.

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Year:  2005        PMID： 16027870     DOI： 10.1007/s10517-005-0311-5

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  1 in total

1.  Binding of tripeptide Pro-Gly-Pro labeled at the C-terminal proline residue to plasma membranes of the rat forebrain.

Authors:  T V V'unova; L A Andreeva; K V Shevchenko; V P Shevchenko; M Yu Bobrov; V V Bezuglov; N F Myasoedov
Journal:  Dokl Biol Sci       Date:  2008 Mar-Apr
  1 in total

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