Literature DB >> 16027861

Effect of insulin on NO production by monocytes from patients with metabolic cardiovascular syndrome.

T E Suslova1, A V Sitozhevskii, O N Ogurkova, O V Gruzdeva, T S Fedorova, R S Karpov.   

Abstract

Basal and insulin-induced production of NO by monocytes significantly increased in patients with metabolic cardiovascular syndrome. Plasma insulin concentration in these patients was below the control. No intergroup differences were found in C-peptide concentration. A negative correlation was revealed between insulin-induced NO production by monocytes and C-peptide/insulin ratio in patients. The role of monocytes on the regulation of vascular tone via NO production in patients with metabolic cardiovascular syndrome is discussed.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 16027861     DOI: 10.1007/s10517-005-0302-6

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  1 in total

Review 1.  Platelet hemostasis in patients with metabolic syndrome and type 2 diabetes mellitus: cGMP- and NO-dependent mechanisms in the insulin-mediated platelet aggregation.

Authors:  Tatiana E Suslova; Alexei V Sitozhevskii; Oksana N Ogurkova; Elena S Kravchenko; Irina V Kologrivova; Yana Anfinogenova; Rostislav S Karpov
Journal:  Front Physiol       Date:  2015-01-05       Impact factor: 4.566

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.