| Literature DB >> 16026784 |
Abstract
Animal models provide a valuable tool for investigating the genetic basis and the pathophysiology of human diseases, and to evaluate therapeutic treatments. To study congenital retinal disorders, mouse mutants have become the most important model organism. Here we review some mouse models, which are related to hereditary disorders (mostly congenital) including retinitis pigmentosa, Leber's congenital amaurosis, macular disorders and optic atrophy.Entities:
Mesh：
Year: 2005 PMID： 16026784 DOI： 10.1016/j.exer.2005.06.004
Source DB: PubMed Journal: Exp Eye Res ISSN： 0014-4835 Impact factor: 3.467