Tao Liu1, Can-hui Wang, Jin Yang. 1. Nanjing University of Traditional Chinese Medicine, Nanjing. liutao@njutcm.edu
Abstract
OBJECTIVE: To investigate the therapeutic effects of modified Sanjiasan decoction (MSD) on vascular dementia (VD). METHODS: Thirty-seven patients in the treated group were given MSD, one dosage each day, and 31 patients in the control group were administered orally Naofukang 0.8 g three times a day. The treatment course for both groups was three months. The indices as Hasegawa dementia scale (HDS), mini mental state examination (MMSE) and its subentries, intelligence quotient (IQ) and memory quotient (MQ) were examined. RESULTS:MSD could improve the scores of HDS, MMSE and its subentries (P<0.05 or P<0.01), ameliorate dementia state and enhance IQ (P<0.05) and MQ (P<0.01) in patients with VD. CONCLUSION:MSD has a certain effect on intelligence benefiting and dementia antagonizing.
RCT Entities:
OBJECTIVE: To investigate the therapeutic effects of modified Sanjiasan decoction (MSD) on vascular dementia (VD). METHODS: Thirty-seven patients in the treated group were given MSD, one dosage each day, and 31 patients in the control group were administered orally Naofukang 0.8 g three times a day. The treatment course for both groups was three months. The indices as Hasegawa dementia scale (HDS), mini mental state examination (MMSE) and its subentries, intelligence quotient (IQ) and memory quotient (MQ) were examined. RESULTS:MSD could improve the scores of HDS, MMSE and its subentries (P<0.05 or P<0.01), ameliorate dementia state and enhance IQ (P<0.05) and MQ (P<0.01) in patients with VD. CONCLUSION:MSD has a certain effect on intelligence benefiting and dementia antagonizing.